glycine dehydrogenase

{{other uses}}

{{infobox enzyme

| Name = glycine dehydrogenase

| EC_number = 1.4.1.10

| CAS_number = 37255-40-6

| GO_code = 0047960

| image =

| width =

| caption =

}}

In enzymology, a glycine dehydrogenase ({{EC number|1.4.1.10}}) is an enzyme that catalyzes the chemical reaction

:glycine + H₂O + NAD⁺ $\backslash rightleftharpoons$ glyoxylate + NH₃ + NADH + H⁺

The 3 substrates of this enzyme are glycine, H₂O, and NAD⁺, whereas its 4 products are glyoxylate, NH₃, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is glycine:NAD+ oxidoreductase (deaminating).

This should not be confused with:

the glycine dehydrogenase (decarboxylating), which is another name for the Glycine cleavage system P-protein ({{EC number|1.4.4.2}}).

or the glycine dehydroganse (cyanide forming)({{EC number|1.4.99.5}}).

or the glycine dehydrogenase (cytochrome) ({{EC number|1.4.2.1}}).