gum guaicum
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| OtherNames = Guaiac resin; Gum guaiac
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| CASNo = 9000-29-7
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| UNII = 570858Q4NE
| EC_number = 232-535-2
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| MeltingPtC = 85-90
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Gum guaicum, or guaiac resin,{{cite web | url = http://www.fao.org/fileadmin/user_upload/jecfa_additives/docs/Monograph1/Additive-216.pdf | title = Guaiac Resin | publisher = Food and Agriculture Organization of the United Nations | date = 2006}} is a substance produced from the tree species Guaiacum officinale. It is registered as food additive: as a preservative under the E number E241, and as an antioxidant under E314.{{Cite web|url=https://www.fao.org/fao-who-codexalimentarius/en/|title=Home : CODEXALIMENTARIUS FAO-WHO|website=Fao.org|access-date=3 April 2022}}
Guaiac resin is also used medically for the stool guaiac test.
Chemically, it is mixture of approximately 70% alpha- and beta-guaiaconic acids, 10% guaiaretic acid, 15% guaiac beta-resin, and small quantities of other chemical compounds such as guaiac yellow and vanillin.