heparin lyase

{{Short description|Enzyme}}

{{infobox enzyme

| Name = heparin lyase

| EC_number = 4.2.2.7

| CAS_number = 9025-39-2

| GO_code = 0047488

| image =

| width =

| caption =

}}

The enzyme heparin lyase ({{EnzExplorer|4.2.2.7}}) catalyzes the following process:

: Eliminative cleavage of polysaccharides containing (1→4)-linked D-glucuronate or L-iduronate residues and (1→4)-α-linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides with terminal 4-deoxy-α-D-gluc-4-enuronosyl groups at their non-reducing ends

This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is heparin lyase. Other names in common use include heparin eliminase, and heparinase.

References

{{reflist|1}}

  • {{cite journal | vauthors = Hovingh P, Linker A | date = 1970 | title = The enzymatic degradation of heparin and heparitin sulfate. 3 Purification of a heparitinase and a heparinase from flavobacteria | journal = J. Biol. Chem. | volume = 245 | pages = 6170–5 | pmid = 5484472 | issue = 22 }}

{{Carbon-oxygen lyases}}

{{Enzymes}}

{{Portal bar|Biology|border=no}}

Category:EC 4.2.2

Category:Enzymes of unknown structure

{{4.2-enzyme-stub}}