heparin lyase
{{Short description|Enzyme}}
{{infobox enzyme
| Name = heparin lyase
| EC_number = 4.2.2.7
| CAS_number = 9025-39-2
| GO_code = 0047488
| image =
| width =
| caption =
}}
The enzyme heparin lyase ({{EnzExplorer|4.2.2.7}}) catalyzes the following process:
: Eliminative cleavage of polysaccharides containing (1→4)-linked D-glucuronate or L-iduronate residues and (1→4)-α-linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides with terminal 4-deoxy-α-D-gluc-4-enuronosyl groups at their non-reducing ends
This enzyme belongs to the family of lyases, specifically those carbon-oxygen lyases acting on polysaccharides. The systematic name of this enzyme class is heparin lyase. Other names in common use include heparin eliminase, and heparinase.
References
{{reflist|1}}
- {{cite journal | vauthors = Hovingh P, Linker A | date = 1970 | title = The enzymatic degradation of heparin and heparitin sulfate. 3 Purification of a heparitinase and a heparinase from flavobacteria | journal = J. Biol. Chem. | volume = 245 | pages = 6170–5 | pmid = 5484472 | issue = 22 }}
{{Carbon-oxygen lyases}}
{{Enzymes}}
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Category:Enzymes of unknown structure
{{4.2-enzyme-stub}}