hydroxynitrilase

{{Short description|Class of enzymes}}

{{infobox enzyme

| Name = acetone-cyanhydrin lyase

| EC_number = 4.1.2.37

| CAS_number = 112567-89-2

| GO_code = 0047606

| image =

| width =

| caption =

}}

In enzymology, a hydroxynitrilase ({{EC number|4.1.2.37}}) is an enzyme that catalyzes the chemical reaction

:acetone cyanohydrin $\backslash rightleftharpoons$ cyanide + acetone

Hence, this enzyme has one substrate, acetone cyanohydrin, and two products, cyanide and acetone.

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is acetone-cyanohydrin acetone-lyase (cyanide-forming). Other names in common use include alpha-hydroxynitrile lyase, hydroxynitrile lyase, acetone-cyanhydrin lyase [mis-spelt], acetone-cyanohydrin acetone-lyase, oxynitrilase, 2-hydroxyisobutyronitrile acetone-lyase, 2-hydroxyisobutyronitrile acetone-lyase (cyanide-forming), and acetone-cyanohydrin lyase.