indobufen

{{Short description|Chemical compound}}

{{Drugbox

| Verifiedfields = changed

| Watchedfields = changed

| verifiedrevid = 447914993

| IUPAC_name = 2-(4-(1-Oxoisoindolin-2-yl)phenyl)butanoic acid

| image = Indobufen structure.svg

| image2 = Indobufen ball-and-stick.png

| tradename =

| Drugs.com = {{drugs.com|international|indobufen}}

| pregnancy_AU =

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| legal_AU =

| legal_CA =

| legal_UK =

| legal_US =

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| routes_of_administration =

| bioavailability =

| protein_bound =

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| CAS_number_Ref = {{cascite|correct|??}}

| CAS_number = 63610-08-2

| ATC_prefix = B01

| ATC_suffix = AC10

| PubChem = 107641

| DrugBank_Ref = {{drugbankcite|correct|drugbank}}

| DrugBank =

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = 6T9949G4LZ

| KEGG_Ref = {{keggcite|correct|kegg}}

| KEGG = D07141

| ChEMBL_Ref = {{ebicite|changed|EBI}}

| ChEMBL = 1765292

| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}

| ChemSpiderID = 96823

| C=18 | H=17 | N=1 | O=3

| smiles = O=C(O)C(c1ccc(cc1)N3C(=O)c2ccccc2C3)CC

| StdInChI_Ref = {{stdinchicite|changed|chemspider}}

| StdInChI = 1S/C18H17NO3/c1-2-15(18(21)22)12-7-9-14(10-8-12)19-11-13-5-3-4-6-16(13)17(19)20/h3-10,15H,2,11H2,1H3,(H,21,22)

| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}

| StdInChIKey = AYDXAULLCROVIT-UHFFFAOYSA-N

}}

Indobufen is a platelet aggregation inhibitor.{{cite book | title = The Merck Index | edition = 12th | page = 4991 }} It acts as a reversible cyclooxygenase inhibitor.{{cite journal | vauthors = Eligini S, Violi F, Banfi C, Barbieri SS, Brambilla M, Saliola M, Tremoli E, Colli S | display-authors = 6 | title = Indobufen inhibits tissue factor in human monocytes through a thromboxane-mediated mechanism | journal = Cardiovascular Research | volume = 69 | issue = 1 | pages = 218–26 | date = January 2006 | pmid = 16154551 | doi = 10.1016/j.cardiores.2005.07.013 | doi-access = free }}