indoline

{{chembox

| Watchedfields = changed

| verifiedrevid = 443873282

| Name = Indoline

| ImageFile = Indoline numbering.svg

| ImageName = Indoline

| ImageFile1 = Indoline3d.png

| ImageName1 = Indoline

| PIN = 2,3-Dihydro-1H-indole

| OtherNames = 2,3-Dihydroindole

|Section1={{Chembox Identifiers

| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}

| ChemSpiderID = 9905

| InChI = 1/C8H9N/c1-2-4-8-7(3-1)5-6-9-8/h1-4,9H,5-6H2

| ChEBI_Ref = {{ebicite|correct|EBI}}

| ChEBI = 43295

| SMILES = c1cccc2c1CCN2

| InChIKey = LPAGFVYQRIESJQ-UHFFFAOYAF

| ChEMBL_Ref = {{ebicite|correct|EBI}}

| ChEMBL = 388803

| StdInChI_Ref = {{stdinchicite|correct|chemspider}}

| StdInChI = 1S/C8H9N/c1-2-4-8-7(3-1)5-6-9-8/h1-4,9H,5-6H2

| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}

| StdInChIKey = LPAGFVYQRIESJQ-UHFFFAOYSA-N

| CASNo_Ref = {{cascite|correct|CAS}}

| CASNo = 496-15-1

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = 6DPT9AB2NK

| PubChem = 10328

| RTECS = NL6906300

| Beilstein = 111915

}}

|Section2={{Chembox Properties

| Appearance = Clear colourless liquid

| Formula = C8H9N

| MolarMass = 119.16 g/mol

| Density = 1.063 g/mL

| MeltingPtC = -21

| BoilingPtC = 220 to 221

| BoilingPt_notes =

}}

|Section7={{Chembox Hazards

| ExternalSDS = [http://fscimage.fishersci.com/msds/27760.htm Fisher Scientific]

| MainHazards =

| NFPA-H =

| NFPA-F =

| NFPA-R =

| FlashPtC = 92.8

}}

|Section8={{Chembox Related

| OtherFunction_label = aromatics

| OtherFunction = carbazole, indole, isoindoline, oxindole

}}

}}

Indoline is an aromatic heterocyclic organic compound with the chemical formulation C8H9N. It has a bicyclic structure, consisting of a six-membered benzene ring fused to a five-membered nitrogen-containing ring. The compound is based on the indole structure, but the 2-3 bond is saturated. By oxidation/dehydrogenation it can be converted to indole.{{Katritzky2nd}}{{cite book |last=Clayden |first=J. |last2=Greeves |first2=N. |last3=Warren |first3=S. |last4=Wothers |first4=P. |title=Organic Chemistry |publisher=Oxford University Press |location=Oxford, Oxfordshire |year=2001 |isbn=0-19-850346-6 |url=https://archive.org/details/organicchemistry00clay_0 |url-access=registration }}

Indoline can be produced from the reaction of indole, zinc and 85% phosphoric acid.{{cite journal | last=Dolby | first=Lloyd J. | last2=Gribble | first2=Gordon W. | title=A convenient preparation of indoline | journal=Journal of Heterocyclic Chemistry | volume=3 | issue=2 | date=1966 | issn=0022-152X | doi=10.1002/jhet.5570030202 | pages=124–125}} It was used to make Indocaine.

References

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