intelectin-2

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

Intelectin 2 is a protein that in humans is encoded by the ITLN2 gene.{{cite web | title = Entrez Gene: Intelectin 2 | url = https://www.ncbi.nlm.nih.gov/gene/142683 | access-date = 2016-02-25

}}

Human intelectin-2 has non-conserved ligand binding site substitutions compared to human intelectin-1, thus these two intelectins may not have the same metal ion requirements and ligand specificity. Likewise, there are also ligand binding site residue variations between human and mouse intelectin-2 with no known biochemical and functional consequences.{{cite journal | vauthors = Wangkanont K, Wesener DA, Vidani JA, Kiessling LL, Forest KT | title = Structures of Xenopus Embryonic Epidermal Lectin Reveal a Conserved Mechanism of Microbial Glycan Recognition | journal = The Journal of Biological Chemistry | volume = 291 | issue = 11 | pages = 5596–610 | date = March 2016 | pmid = 26755729 | doi = 10.1074/jbc.M115.709212 | pmc = 4786701 | doi-access = free }}

See also

References

{{reflist}}

{{gene-1-stub}}