iotalamic acid
{{short description|Chemical compound}}
{{Use dmy dates|date=February 2022}}
{{Infobox drug
| type =
| image = Iotalamic acid.png
| width = 200
| alt = Skeletal formula of iotalamic acid
| image2 = Iotalamic-acid-3D-spacefill.png
| width2 = 180
| alt2 = Space-filling model of the iotalamic acid molecule
| caption =
| USAN = Iothalamic acid
| pronounce =
| tradename = Conray, Glofil-125, Cysto-Conray II, others
| Drugs.com = {{drugs.com|cdi|iothalamate-meglumine}}
| MedlinePlus =
| licence_EU =
| DailyMedID = Iothalamate
| licence_US =
| pregnancy_AU =
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| routes_of_administration = Intravascular
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| ATCvet =
| ATC_prefix = V08
| ATC_suffix = AA04
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| legal_US = Rx-only
| legal_US_comment = {{cite web | title=Conray- iothalamate meglumine injection | website=DailyMed | date=1 January 2021 | url=https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1292abfc-496f-4df7-9a08-72072953e1f1 | access-date=23 February 2022}}{{cite web | title=Glofil-125- sodium iothalamate i-125 injection injection, solution | website=DailyMed | date=9 December 2019 | url=https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7f250086-2837-484b-9674-e09856b34cb0 | access-date=23 February 2022}}{{cite web | title=Cysto-Conray II- iothalamate meglumine injection | website=DailyMed | date=31 December 2020 | url=https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=8841ab4d-674d-4beb-88a5-13e35f6005cc | access-date=23 February 2022}}
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| CAS_number = 2276-90-6
| CAS_supplemental =
| PubChem = 3737
| IUPHAR_ligand =
| DrugBank = DB09133
| ChemSpiderID = 3606
| UNII = 16CHD79MIX
| KEGG = D01258
| ChEBI = 31713
| ChEMBL = 1201300
| NIAID_ChemDB =
| PDB_ligand =
| synonyms = MI-216, iothalamate meglumine
| IUPAC_name = 3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid
| C=11 | H=9 | I=3 | N=2 | O=4
| SMILES = CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)C(=O)NC)I
| StdInChI = 1S/C11H9I3N2O4/c1-3(17)16-9-7(13)4(10(18)15-2)6(12)5(8(9)14)11(19)20/h1-2H3,(H,15,18)(H,16,17)(H,19,20)
| StdInChI_comment =
| StdInChIKey = UXIGWFXRQKWHHA-UHFFFAOYSA-N
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Iotalamic acid, sold under the brand name Conray, is an iodine-containing radiocontrast agent. It is available in form of its salts, sodium iotalamate and meglumine iotalamate. It can be given intravenously or intravesically (into the urinary bladder).
A radioactive formulation is also available as sodium iothalamate I-125 injection (brand name Glofil-125). It is indicated for evaluation of glomerular filtration in the diagnosis or monitoring of people with kidney disease.
References
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External links
- {{cite web | url = https://druginfo.nlm.nih.gov/drugportal/name/iothalamate%20meglumine | publisher = U.S. National Library of Medicine | work = Drug Information Portal | title = Iothalamate meglumine }}
- {{cite web | url = https://druginfo.nlm.nih.gov/drugportal/name/iothalamate%20sodium | publisher = U.S. National Library of Medicine | work = Drug Information Portal | title = Iothalamate sodium }}
{{Contrast media}}
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Category:Iodobenzene derivatives
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