ioxilan
{{Short description|Chemical compound}}
{{Drugbox
| Verifiedfields = changed
| verifiedrevid = 461935346
| IUPAC_name = 1-N-(2,3-dihydroxypropyl)-5-[N-(2,3-dihydroxypropyl)acetamido]-3-N-(2-hydroxyethyl)-2,4,6-triiodobenzene-1,3-dicarboxamide
| image = Ioxilan structure.png
| tradename = Oxilan
| Drugs.com = {{drugs.com|pro|oxilan}}
| pregnancy_AU =
| pregnancy_US = B
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US = Rx-only
| legal_status = Discontinued
| routes_of_administration = intravenously
| bioavailability = N/A
| protein_bound = negligible
| metabolism = none
| elimination_half-life = 2 hours
| excretion = Mostly renal
| CAS_number_Ref = {{cascite|changed|??}}
| CAS_number = 107793-72-6
| ATC_prefix = V08
| ATC_suffix = AB12
| PubChem = 3743
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank = DB09135
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 3612
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = A4YJ7J11TG
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D02161
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 1201075
| C=18 | H=24 | I=3 | N=3 | O=8
| smiles = O=C(N(c1c(I)c(c(I)c(c1I)C(=O)NCCO)C(=O)NCC(O)CO)CC(O)CO)C
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C18H24I3N3O8/c1-8(28)24(5-10(30)7-27)16-14(20)11(17(31)22-2-3-25)13(19)12(15(16)21)18(32)23-4-9(29)6-26/h9-10,25-27,29-30H,2-7H2,1H3,(H,22,31)(H,23,32)
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = UUMLTINZBQPNGF-UHFFFAOYSA-N
}}
Ioxilan is a diagnostic contrast agent.{{cite book | vauthors = Cheng KT | chapter = Ioxilan carbonate particles | title = Molecular Imaging and Contrast Agent Database (MICAD) [Internet] | location = Bethesda (MD) | publisher = National Center for Biotechnology Information (US) | date = December 2007 | pmid = 20641969 | doi = | chapter-url = https://www.ncbi.nlm.nih.gov/books/NBK25587/ }} It is injected intravenously before taking X-ray images to increase arterial contrast in the final image. It was marketed in the US under the trade name Oxilan by Guerbet, L.L.C., but was discontinued in 2017.Oxilan {{drugs.com|pro|oxilan}}. Accessed 2021-04-07.
Mechanism of action
Ioxilan is an iodinated contrast agent.