methantheline
{{Short description|Chemical compound}}
{{notability|date=March 2017}}
{{Drugbox
| Verifiedfields = changed
| Watchedfields = changed
| class = Antimuscarinic
| verifiedrevid = 376104968
| IUPAC_name = N,N-diethyl-N-methyl-2-[(9H-xanthen-9-ylcarbonyl)oxy]-ethanaminium
| image = methantheline.png
| tradename = Banthine, Vagantil, others
| Drugs.com =
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| legal_status =
| routes_of_administration = By mouth
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 5818-17-7
| ATC_prefix = A03
| ATC_suffix = AB07
| PubChem = 4097
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank =
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 3955
| UNII_Ref = {{fdacite|changed|FDA}}
| UNII = 36EI79TX7I
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 1201264
| C = 21
| H = 26
| N = 1
| O = 3
| smiles = CC[N+](C)(CC)CCOC(=O)C1C2=CC=CC=C2OC3=CC=CC=C13
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI = 1S/C21H26NO3/c1-4-22(3,5-2)14-15-24-21(23)20-16-10-6-8-12-18(16)25-19-13-9-7-11-17(19)20/h6-13,20H,4-5,14-15H2,1-3H3/q+1
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
| StdInChIKey = GZHFODJQISUKAY-UHFFFAOYSA-N
}}
Methantheline is an antimuscarinic.{{cite journal | vauthors = McHardy GG, Browne DC, Marek FH, McHardy R, Ward S | title = Clinical evaluation of methantheline (banthine) bromide in gastroenterology | journal = Journal of the American Medical Association | volume = 147 | issue = 17 | pages = 1620–6 | date = December 1951 | pmid = 14880413 | doi = 10.1001/jama.1951.03670340010003 }}
References
{{Reflist}}
{{Drugs for functional gastrointestinal disorders}}
{{Muscarinic acetylcholine receptor modulators}}
Category:Muscarinic antagonists
Category:Quaternary ammonium compounds
{{gastrointestinal-drug-stub}}