microvascular occlusion
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Microvascular occlusion refers to conditions that can present with retiform purpura.{{cite book|author1=Jean L. Bolognia|author2=Joseph L. Jorizzo|author3=Ronald P. Rapini|title=Dermatology|url=https://books.google.com/books?id=f2IwYiyh3YUC&pg=PT390|accessdate=20 May 2011|date=27 August 2003|publisher=Elsevier Health Sciences|isbn=978-0-323-02578-2|pages=390–}} It has been suggested that phenylephrine may be a cause.{{Cite journal | last1 = Kalajian | first1 = AH. | last2 = Turpen | first2 = KB. | last3 = Donovan | first3 = KO. | last4 = Malone | first4 = JC. | last5 = Callen | first5 = JP. | title = Phenylephrine-induced microvascular occlusion syndrome in a patient with a heterozygous factor V Leiden mutation | journal = Arch Dermatol | volume = 143 | issue = 10 | pages = 1314–7 |date=Oct 2007 | doi = 10.1001/archderm.143.10.1314 | pmid = 17938347 | doi-access = free }}
Signs and symptoms
Microvascular occlusions appears as bland necrosis without inflammation and retiform purpura.{{cite journal | last=Dehghani | first=Shakiba | last2=Abtahi-Naeini | first2=Bahareh | title=COVID-19: A new cause of cutaneous microvascular occlusion syndrome | journal=Journal of Research in Medical Sciences | publisher=Medknow | volume=26 | issue=1 | year=2021 | issn=1735-1995 | doi=10.4103/jrms.jrms_560_21 | doi-access=free | page=119| pmc=8765522 }}
Causes
Microvascular occlusions can be caused by heparin-induced thrombocytopenia, cryoglobulinemia, angioinvasive organisms, embolization, disseminated intravascular coagulation, livedoid vasculopathy, cell occlusion syndromes, and iatrogenic causes.
Outlook
References
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Further reading
- {{cite journal | last=Hosseini | first=Nastaran-Sadat | last2=Babaei | first2=Sharareh | last3=Rahimi | first3=Hamid | last4=Gheissari | first4=Alaleh | last5=Sedaghat | first5=Banafsheh | last6=Pourmahdi-Boroujeni | first6=Mahsa | last7=Abtahi-Naeini | first7=Bahareh | title=Cutaneous microvascular occlusion syndrome as the first manifestation of catastrophic lupus-associated antiphospholipid antibody syndrome: a case report | journal=Journal of Medical Case Reports | volume=17 | issue=1 | date=2023-08-22 | issn=1752-1947 | pmid=37605287 | pmc=10464427 | doi=10.1186/s13256-023-04068-9 | doi-access=free | ref=none}}
- {{cite journal | last=Ko | first=Christine J. | last2=Gehlhausen | first2=Jeff R. | last3=McNiff | first3=Jennifer M. | title=Leukocytoclastic Vasculitis and Microvascular Occlusion | journal=Surgical Pathology Clinics | publisher=Elsevier BV | volume=14 | issue=2 | year=2021 | issn=1875-9181 | doi=10.1016/j.path.2021.01.006 | pages=309–325 | ref=none}}
External links
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{{Cutaneous vasculitis}}