mir-320

{{Infobox rfam

| Name = mir-320

| image = RF00736.png

| width =

| caption = Conserved secondary structure of mir-320

| Symbol = mir-320

| AltSymbols =

| Rfam = RF00736

| miRBase_family = MIPF0000163

| RNA_type = microRNA

| Tax_domain = Eukaryota;

| HGNCid =

| OMIM =

}}

In molecular biology mir-320 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by several mechanisms.

The biogenesis of miR-320 is different from the canonical microprocessor-dependent miRNAs. The pre-miR-320 is transcribed directly as a precursor microRNA hairpin and thus contains a 5′ m7G-cap.

References

{{cite journal |vauthors=Xia HF, Jin XH, Song PP, Cui Y, Liu CM, Ma X |title=Temporal and spatial regulation of miR-320 in the uterus during embryo implantation in the rat. |journal=Int J Mol Sci |volume=11 |issue=2 |pages=719–730 |year=2010 |pmid=20386663 |doi=10.3390/ijms11020719 |pmc=2852863|doi-access=free }}

{{cite journal |vauthors=Duan H, Jiang Y, Zhang H, Wu Y |title=MiR-320 and miR-494 affect cell cycles of primary murine bronchial epithelial cells exposed to benzo[a]pyrene |journal=Toxicol in Vitro |volume=24 |issue=3 |pages=928–935 |year=2010 |pmid=19925859 |doi=10.1016/j.tiv.2009.11.013}}

{{cite journal |vauthors=Ling HY, Ou HS, Feng SD, Zhang XY, Tuo QH, Chen LX, Zhu BY, Gao ZP, Tang CK, Yin WD, Zhang L, Liao DF |title=Changes in microRNA profile and effects of miR-320 in insulin-resistant 3T3-L1 adipocytes |journal=Clin Exp Pharmacol Physiol |volume= 36|issue= 9|pages= e32–e39|year=2009 |pmid=19473196 |doi=10.1111/j.1440-1681.2009.05207.x|s2cid=10568446 }}

{{cite journal |vauthors=Ren XP, Wu J, Wang X, Sartor MA, Qian J, Jones K, Nicolaou P, Pritchard TJ, Fan GC |title=MicroRNA-320 is involved in the regulation of cardiac ischemia/reperfusion injury by targeting heat-shock protein 20 |journal=Circulation |volume=119 |issue=17 |pages=2357–2366 |year=2009 |pmid=19380620 |doi=10.1161/CIRCULATIONAHA.108.814145 |pmc=2746735}}

{{cite journal |vauthors=Schaar DG, Medina DJ, Moore DF, Strair RK, Ting Y |title=miR-320 targets transferrin receptor 1 (CD71) and inhibits cell proliferation |journal=Exp Hematol |volume=37 |issue=2 |pages=245–255 |year=2009 |pmid=19135902 |doi=10.1016/j.exphem.2008.10.002|doi-access=free }}

{{cite journal |vauthors=Wang XH, Qian RZ, Zhang W, Chen SF, Jin HM, Hu RM |title=MicroRNA-320 expression in myocardial microvascular endothelial cells and its relationship with insulin-like growth factor-1 in type 2 diabetic rats |journal=Clin Exp Pharmacol Physiol |volume=36 |issue=2 |pages=181–188 |year=2009 |pmid=18986336 |doi=10.1111/j.1440-1681.2008.05057.x|s2cid=205458045 }}

{{cite journal|last=Ling|first=HY |author2=Ou, HS |author3=Feng, SD |author4=Zhang, XY |author5=Tuo, QH |author6=Chen, LX |author7=Zhu, BY |author8=Gao, ZP |author9=Tang, CK |author10=Yin, WD |author11=Zhang, L |author12=Liao, DF|title=CHANGES IN microRNA (miR) profile and effects of miR-320 in insulin-resistant 3T3-L1 adipocytes.|journal=Clinical and Experimental Pharmacology & Physiology|date=September 2009|volume=36|issue=9|pages=e32–9|pmid=19473196|doi=10.1111/j.1440-1681.2009.05207.x|s2cid=10568446 }}

{{cite journal|last=Xie|first=M |author2=Li, M |author3=Vilborg, A |author4=Lee, N |author5=Yartseva, V |author6=Sestan, N |author7=Steitz, J |title=Mammalian 5′-Capped MicroRNA Precursors that Generate a Single MicroRNA.|journal=Cell|date=September 2013|volume=155|issue=7|pages=1568–1580|pmid=24360278 |doi=10.1016/j.cell.2013.11.027 |pmc=3899828}}

External links

{{Rfam|id=RF00736|name=mir-320 microRNA precursor family}}

Category:MicroRNA

Category:Non-coding RNA