molvizarin

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| ImageFile = Molvizarin.svg

| ImageSize = 200px

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| IUPACName = (2S)-4-[(2R,11R)-2,11-Dihydroxy-11-[(2R,5R)-5-[(2R,5R)-5-[(1S)-1-hydroxyundecyl]oxolan-2-yl]oxolan-2-yl]undecyl]-2-methyl-2H-furan-5-one{{cite journal |title=Molvizarin |journal=Pubchem.ncbi.NLM.nih.gov |url=https://pubchem.ncbi.nlm.nih.gov/compound/Molvizarin#section=3D-Status |language=en}}

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| CASNo = 138551-26-5

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| ChEBI =

| ChEMBL = 110333

| ChemSpiderID = 23193544

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| PubChem = 44337885

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| StdInChI=1S/C35H62O7/c1-3-4-5-6-7-8-12-15-18-29(37)31-20-22-33(41-31)34-23-21-32(42-34)30(38)19-16-13-10-9-11-14-17-28(36)25-27-24-26(2)40-35(27)39/h24,26,28-34,36-38H,3-23,25H2,1-2H3/t26-,28+,29-,30+,31+,32+,33+,34+/m0/s1

| StdInChIKey = YVZIPERWMPDEIZ-XDBACSEOSA-N

| SMILES = CCCCCCCCCC[C@@H]([C@H]1CC[C@@H](O1)[C@H]2CC[C@@H](O2)[C@@H](CCCCCCCC[C@H](CC3=C[C@@H](OC3=O)C)O)O)O

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| Section2 = {{Chembox Properties

| C=35 | H=62 | O=7

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Molvizarin is a cytotoxic acetogenin derivate with the molecular formula C35H62O7 which has been isolated from the bark of the plant Annona cherimolia.{{cite book |last1=Kintzios |first1=Spiridon E. |last2=Barberaki |first2=Maria G. |title=Plants that Fight Cancer |date=15 January 2004 |publisher=CRC Press |isbn=978-1-4200-2371-8 |page=79 |language=en}}{{cite journal |last1=Cortes |first1=Diego |last2=Myint |first2=Saw H. |last3=Hocquemiller |first3=Reynald |title=Molvizarin and motrilin: Two novel cytotoxic bis-tetrahydro-furanic γ-lactone acetogenins from Annona cherimolia |journal=Tetrahedron |date=September 1991 |volume=47 |issue=38 |pages=8195–8202 |doi=10.1016/s0040-4020(01)91014-2}}{{cite book |last1=Xu |first1=Jun-Ping |title=Cancer Inhibitors from Chinese Natural Medicines |date=25 November 2016 |publisher=CRC Press |isbn=978-1-315-34923-7 |url=https://books.google.com/books?id=elFIDgAAQBAJ&dq=Molvizarin&pg=PT274 |language=en}}{{cite book |title=Issues in Materials and Manufacturing Research: 2011 Edition |date=9 January 2012 |publisher=ScholarlyEditions |isbn=978-1-4649-6331-5 |page=5103 |language=en}} Molvizarin has in vitro activity against tumor cells.{{cite journal |last1=Nakanishi |first1=Yuka |last2=Chang |first2=Fang-Rong |last3=Liaw |first3=Chih-Chuang |last4=Wu |first4=Yang-Chang |last5=Bastow |first5=Kenneth F. |last6=Lee |first6=Kuo-Hsiung |title=Acetogenins as Selective Inhibitors of the Human Ovarian 1A9 Tumor Cell Line |journal=Journal of Medicinal Chemistry |date=1 July 2003 |volume=46 |issue=15 |pages=3185–3188 |doi=10.1021/jm020548b|pmid=12852747 }}

References

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Category:Polyketides

Category:Lactones

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