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monocarboxylate transporter 10

{{Short description|Protein found in humans}}

{{Infobox_gene}}

Monocarboxylate transporter 10 (MCT 10), also known as aromatic amino acid transporter 1 and T-type amino acid transporter 1 (TAT1) and solute carrier family 16 member 10 (SLC16A10), is a protein that in humans is encoded by the SLC16A10 gene.{{cite web | title = Entrez Gene: solute carrier family 16| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=117247}}{{cite journal | vauthors = Kim DK, Kanai Y, Chairoungdua A, Matsuo H, Cha SH, Endou H | title = Expression cloning of a Na+-independent aromatic amino acid transporter with structural similarity to H+/monocarboxylate transporters | journal = J. Biol. Chem. | volume = 276 | issue = 20 | pages = 17221–8 |date=May 2001 | pmid = 11278508 | doi = 10.1074/jbc.M009462200 | doi-access = free }}{{cite journal | vauthors = Kim DK, Kanai Y, Matsuo H, Kim JY, Chairoungdua A, Kobayashi Y, Enomoto A, Cha SH, Goya T, Endou H | title = The human T-type amino acid transporter-1: characterization, gene organization, and chromosomal location | journal = Genomics | volume = 79 | issue = 1 | pages = 95–103 |date=January 2002 | pmid = 11827462 | doi = 10.1006/geno.2001.6678 }} SLC16A10 is a member of the solute carrier family.

Function

SLC16A10 mediates Na+-independent transport of tryptophan, tyrosine, phenylalanine, and L-DOPA.

See also

References

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Further reading

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  • {{cite journal |vauthors=Toure A, Morin L, Pineau C, etal |title=Tat1, a novel sulfate transporter specifically expressed in human male germ cells and potentially linked to rhogtpase signaling. |journal=J. Biol. Chem. |volume=276 |issue= 23 |pages= 20309–15 |year= 2001 |pmid= 11278976 |doi= 10.1074/jbc.M011740200 |doi-access= free }}
  • {{cite journal |vauthors=Friesema EC, Jansen J, Jachtenberg JW, etal |title=Effective cellular uptake and efflux of thyroid hormone by human monocarboxylate transporter 10. |journal=Mol. Endocrinol. |volume=22 |issue= 6 |pages= 1357–69 |year= 2008 |pmid= 18337592 |doi= 10.1210/me.2007-0112 |pmc= 5419535 }}
  • {{cite journal |vauthors= Loubière LS, Vasilopoulou E, Bulmer JN |title= Expression of thyroid hormone transporters in the human placenta and changes associated with intrauterine growth restriction. |journal= Placenta |volume= 31 |issue= 4 |pages= 295–304 |year= 2010 |pmid= 20167367 |doi= 10.1016/j.placenta.2010.01.013 |display-authors= etal |url= http://www.zora.uzh.ch/id/eprint/33687/3/Stieger_TH_transporters-2.pdf |access-date= 2019-08-16 |archive-date= 2021-05-03 |archive-url= https://web.archive.org/web/20210503101022/https://www.zora.uzh.ch/id/eprint/33687/3/Stieger_TH_transporters-2.pdf |url-status= dead }}
  • {{cite journal |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2002 |pmid= 12477932 |pmc=139241 |doi= 10.1073/pnas.242603899 |bibcode=2002PNAS...9916899M |doi-access=free }}
  • {{cite journal |author=Bröer S |title=Amino acid transport across mammalian intestinal and renal epithelia. |journal=Physiol. Rev. |volume=88 |issue=1 |pages=249–86 |year=2008 |pmid=18195088 |doi=10.1152/physrev.00018.2006 |s2cid=1834804 |url=https://semanticscholar.org/paper/0ed966360f9302bb910bbe0daa17aea6da1258f9 }}
  • {{cite journal |vauthors=Park SY, Kim JK, Kim IJ, etal |title=Reabsorption of neutral amino acids mediated by amino acid transporter LAT2 and TAT1 in the basolateral membrane of proximal tubule. |journal=Arch. Pharm. Res. |volume=28 |issue= 4 |pages= 421–32 |year= 2005 |pmid= 15918515 |doi= 10.1007/BF02977671|s2cid=2139640 }}
  • {{cite journal |vauthors=Halestrap AP, Meredith D |title=The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. |journal=Pflügers Arch. |volume=447 |issue= 5 |pages= 619–28 |year= 2004 |pmid= 12739169 |doi= 10.1007/s00424-003-1067-2 |s2cid=15498611 }}

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{{solute carrier family}}

Category:Solute carrier family

Category: Thyroid hormone transporters

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