narK RNA motif

{{primary sources|date=November 2021}}

{{DISPLAYTITLE:narK RNA motif}}

{{Infobox rfam

| Name = narK

| image = RF03032.svg

| width =

| caption = Consensus secondary structure and sequence conservation of narK RNA

| Symbol = narK

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| Rfam = RF03032

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| RNA_type = Cis-reg

| Tax_domain =

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| SO = {{SO|0005836}}

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| EntrezGene =

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The narK RNA motif is a conserved RNA structure that was discovered by bioinformatics.{{cite journal |vauthors=Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR |title=Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions |journal=Nucleic Acids Res. |volume=45 |issue=18 |pages=10811–10823 |date=October 2017 |pmid=28977401 |pmc=5737381 |doi=10.1093/nar/gkx699 }}

narK motif RNAs are found in Beta- and Gammaproteobacteria.

narK RNAs likely function as cis-regulatory elements, in view of their positions upstream of protein-coding genes. Four genes are presumably regulated by narK RNA, and they encode: a nitrate transporter, proteins with sulfite- and nitrate reductase domains, proteins in the major facilitator superfamily and cyclic di-GMP-specific phosphodiesterases of the EAL family. It was therefore proposed that there is good evidence that narK RNAs regulate genes in cis, and that they might play a role related to nitrate.

References