nhaA-II RNA motif

{{primary sources|date=November 2021}}

{{DISPLAYTITLE:nhaA-II RNA motif}}

{{Infobox rfam

| Name = nhaA-II

| image = RF03038.svg

| width =

| caption = Consensus secondary structure and sequence conservation of nhaA-II RNA

| Symbol = nhaA-II

| AltSymbols =

| Rfam = RF03038

| miRBase =

| miRBase_family =

| RNA_type = Cis-reg

| Tax_domain =

| GO =

| SO = {{SO|0005836}}

| CAS_number =

| EntrezGene =

| HGNCid =

| OMIM =

| RefSeq =

| Chromosome =

| Arm =

| Band =

| LocusSupplementaryData =

}}

The nhaA-II RNA motif is a conserved RNA structure that was discovered by bioinformatics.{{cite journal |vauthors=Weinberg Z, Lünse CE, Corbino KA, Ames TD, Nelson JW, Roth A, Perkins KR, Sherlock ME, Breaker RR |title=Detection of 224 candidate structured RNAs by comparative analysis of specific subsets of intergenic regions |journal=Nucleic Acids Res. |volume=45 |issue=18 |pages=10811–10823 |date=October 2017 |pmid=28977401 |pmc=5737381 |doi=10.1093/nar/gkx699 }}

nhaA-II motifs are found in Caulobacterales.

nhaA-II motif RNAs likely function as cis-regulatory elements, in view of their positions upstream of protein-coding genes. nhaA-I RNAs typically occur upstream of genes that encode exchangers of sodium ions and protons. More rarely, they also exist upstream of methyltransferases that use S-adenosylmethionine as a donor.

References