nodosome

Nodosome refers to protein complexes involving pattern recognition receptors and intracellular pathogen sensors NOD2 and CARD8. Their activation leads to regulation of caspase-1 and NF-kappa-B.{{cite web|title=nodosome - COPE|url=http://www.copewithcytokines.org/cope.cgi?key=nodosome|accessdate=7 December 2013}}