octadecanoid pathway

File:Jasmonic acid structure.png

File:ALAnumbering.svg

The octadecanoid pathway is a biosynthetic pathway for the production of the phytohormone jasmonic acid (JA), an important hormone for induction of defense genes. JA is synthesized from alpha-linolenic acid, which can be released from the plasma membrane by certain lipase enzymes. For example, in the wound defense response, phospholipase C will cause the release of alpha-linolenic acid for JA synthesis.

In the first step, alpha-linolenic acid is oxidized by the enzyme lipoxygenase. This forms 13-hydroperoxylinolenic acid, which is then modified by a dehydrase and undergoes cyclization by allene oxide cyclase to form 12-oxo-phytodienoic acid. This undergoes reduction and three rounds of beta oxidation to form jasmonic acid.[http://bldg6.arsusda.gov/benlab/Soybean%20Defense%20Response/jasmonic_acid_synthesis.htm Jasmonic Acid Synthesis]

Footnotes

References

  • {{cite book

| title = Plant Hormones: Physiology, Biochemistry and Molecular Biology

| publisher = Kluwer Academic Press

| date =30 April 1995

| location =

| pages = 836

| isbn = 978-0-7923-2985-5

| author = Peter J Davies}}

  • {{cite journal

| title = Fatty acid-derived signals in plants

| author = Hans Weber

| journal = Trends in Plant Science

| year = 2002

| volume = 7

| issue = 5

| pages = 217–224

| doi = 10.1016/S1360-1385(02)02250-1

| pmid = 11992827

}}

Category:Metabolic pathways

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