odulimomab

{{Short description|Pharmaceutical drug}}

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| Verifiedfields = changed

| verifiedrevid = 458283716

| type = mab

| mab_type = mab

| source = o

| target = CD11a

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| CAS_number_Ref = {{cascite|correct|CAS}}

| CAS_number = 159445-64-4

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| UNII = 39R9XU694M

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Odulimomab is an investigational drug for the prevention of transplant rejection{{cite journal | vauthors = Martin X, Da Silva M, Virieux SR, Hadj Aissa A, Buffet R, Tiollier J, Dubernard JM | title = Protective effect of an anti-LFA 1 monoclonal antibody (odulimomab) on renal damage due to ischemia and kidney autotransplantation | journal = Transplantation Proceedings | volume = 32 | issue = 2 | pages = 481 | date = March 2000 | pmid = 10715487 | doi = 10.1016/S0041-1345(00)00849-6 }}{{cite journal | vauthors = Crétolle-Vastel C, Camby C, Cerf-Bensussan N, Cavazzana-Calvo M, Fischer A, Révillon Y, Sarnacki S | title = [Role of calcineurin-dependent drugs on the immunosuppressive effect induced by the anti-LFA-1 antibody in a fetal intestinal transplantation model in mice] | journal = Chirurgie; Mémoires de l'Académie de Chirurgie | volume = 124 | issue = 5 | pages = 503–10 | date = November 1999 | pmid = 10615777 | doi = 10.1016/s0001-4001(00)88272-0 }} and for the treatment of various immunological diseases.{{cite journal | vauthors = Whitcup SM, Chan CC, Kozhich AT, Magone MT | title = Blocking ICAM-1 (CD54) and LFA-1 (CD11a) inhibits experimental allergic conjunctivitis | journal = Clinical Immunology | volume = 93 | issue = 2 | pages = 107–13 | date = November 1999 | pmid = 10527686 | doi = 10.1006/clim.1999.4775 }}{{cite journal | vauthors = Corbascio M, Mahanty H, Osterholm C, Qi Z, Pearson TC, Larsen CP, Freise CE, Ekberg H | display-authors = 6 | title = Anti-lymphocyte function-associated antigen-1 monoclonal antibody inhibits CD40 ligand-independent immune responses and prevents chronic vasculopathy in CD40 ligand-deficient mice | journal = Transplantation | volume = 74 | issue = 1 | pages = 35–41 | date = July 2002 | pmid = 12134096 | doi = 10.1097/00007890-200207150-00007 | s2cid = 35637410 | doi-access = free }}

It is a mouse monoclonal antibody directed against the alpha chain of the protein lymphocyte function-associated antigen 1 which is involved in immune reactions.