oligonucleotidase

{{Short description|Class of enzymes}}

{{Infobox enzyme

| Name = Oligonucleotidase

| EC_number = 3.1.13.3

| CAS_number = 37288-23-6

| GO_code =

| image =

| width =

| caption =

}}

Oligonucleotidase ({{EC number|3.1.13.3}}, oligoribonuclease) is an exoribonuclease derived from Flammulina velutipes.{{cite journal |vauthors=Kurosawa S, Shimabuku AM, Ishizawa H, Sen K |title=Oligonucleotidase activity of phosphodiesterase from the fruit body of Flammulina velutipes |journal=Agric. Biol. Chem. |volume=54 |issue=3 |pages=587–92 |year=1990 |pmid=1369259 |doi=10.1271/bbb1961.54.587|doi-access=free }} This enzyme catalyses the following chemical reaction

: 3'-end directed exonucleolytic cleavage of viral RNA-DNA hybrid