p-Anisidine

{{DISPLAYTITLE:p-Anisidine}}

{{chembox

| Verifiedfields = changed

| Watchedfields = changed

| verifiedrevid = 414442906

| Name = p-Anisidine

| ImageFileL1 = 4-Anisidine.png

| ImageSizeL1 = 90px

| ImageAltL1 = Skeletal formula of p-anisidine

| ImageFileR1 = P-Anisidine 3D ball.png

| ImageSizeR1 = 110px

| ImageAltR1 = Ball-and-stick model of p-anisidine

| PIN = 4-Methoxyaniline{{cite book | title = Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book) | publisher = The Royal Society of Chemistry | date = 2014 | location = Cambridge | page = 669 | doi = 10.1039/9781849733069-00648 | isbn = 978-0-85404-182-4 | quote = The names ‘toluidine’, ‘anisidine’, and ‘phenetidine’ for which o-, m-, and p- have been used to distinguish isomers, and ‘xylidine’ for which numerical locants, such as 2,3-, have been used, are no longer recommended, nor are the corresponding prefixes ‘toluidine’, ‘anisidino’, ‘phenetidine’, and ‘xylidino’.}}

| OtherNames = para-Anisidine; 4-Aminoanisole; p-Aminoanisole

|Section1={{Chembox Identifiers

| InChI = 1/C7H9NO/c1-9-7-4-2-6(8)3-5-7/h2-5H,8H2,1H3

| ChEMBL_Ref = {{ebicite|correct|EBI}}

| ChEMBL = 295652

| ChEBI = 82388

| StdInChI_Ref = {{stdinchicite|correct|chemspider}}

| StdInChI = 1S/C7H9NO/c1-9-7-4-2-6(8)3-5-7/h2-5H,8H2,1H3

| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}

| StdInChIKey = BHAAPTBBJKJZER-UHFFFAOYSA-N

| SMILES = COc1ccc(cc1)N

| CASNo = 104-94-9

| CASNo_Ref = {{cascite|correct|CAS}}

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = 575917SNR4

| EC_number = 203-254-2

| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}

| ChemSpiderID = 13869414

| KEGG_Ref = {{keggcite|correct|kegg}}

| KEGG = C19326

| PubChem = 7732

| RTECS = BZ5450000

| UNNumber = 2431

}}

|Section2={{Chembox Properties

| Properties_ref = {{RubberBible62nd|page=C-98}}

| Appearance = Light reddish brown solid

| Odor = Fishy

| C=7 | H=9 | N=1 | O=1

| MeltingPtC = 56 to 59

| MeltingPt_notes =

| BoilingPtC = 243

| Density = 1.071 (at 57 °C)

| RefractIndex = 1.5559

| Solubility = Sparingly soluble

| SolubleOther = Soluble in ethanol, diethyl ether, acetone, benzene

| Solvent = other solvents

| VaporPressure = 0.006 mmHg (25 °C)

| MagSus = −80.56·10⁻⁶ cm³/mol

}}

|Section7={{Chembox Hazards

| MainHazards= Carcinogen

| FlashPtC = 122

| AutoignitionPtC = 515

| GHSPictograms = {{GHS06}}{{GHS08}}{{GHS09}}

| GHSSignalWord = Warning

| HPhrases = {{H-phrases|300|310|330|350|373|400}}{{cite web|url=https://pubchem.ncbi.nlm.nih.gov/compound/p-Anisidine#section=Safety-and-Hazards|title=p-Anisidine safety and hazards|access-date=2022-12-02|website=pubchem.ncbi.nlm.nih.gov}}

| PPhrases = {{P-phrases|201|202|260|262|264|270|271|273|280|281|284|301+310|302+350|304+340|308+313|310|314|320|321|322|330|361|363|391|403+233|405|501}}

| PEL = TWA 0.5 mg/m³ [skin]{{PGCH|0035}}

| IDLH = 50 mg/m³

| REL = TWA 0.5 mg/m³ [skin]

| LD50 = 145 mg/kg (rabbit, oral)p-Anisidine toxicity
130 mg/kg (mouse, oral)
140 mg/kg (rat, oral){{IDLH|104949|p-Anisidine}}

| LDLo = 100 mg/kg (mouse, oral)

}}

|Section8={{Chembox Related

| OtherCompounds = o-Anisidine
m-Anisidine

}}

}}

p-Anisidine (or para-anisidine) is an organic compound with the formula CH₃OC₆H₄NH₂. A white solid, commercial samples can appear grey-brown owing to air oxidation. It is one of three isomers of anisidine, methoxy-containing anilines. It is prepared by reduction of 4-nitroanisole.{{cite encyclopedia|last1=Mitchell|first1=Stephen C.|last2=Waring|first2=Rosemary H.|chapter=Aminophenols|encyclopedia=Ullmann's Encyclopedia of Industrial Chemistry|publisher=Wiley-VCH|year=2000|doi=10.1002/14356007.a02_099|isbn=3527306730}}