pentorex

{{Short description|Chemical compound}}

{{Drugbox

| Verifiedfields = changed

| Watchedfields = changed

| verifiedrevid = 437183410

| image = Pentorex.svg

| width =

| tradename = Modatrop

| pregnancy_category =

| legal_status =

| legal_US = Schedule I (positional isomer of Etilamfetamine){{cn|date=February 2024}}

| routes_of_administration =

| bioavailability =

| protein_bound =

| metabolism =

| elimination_half-life =

| excretion =

| CAS_number_Ref = {{cascite|correct|??}}

| CAS_number = 434-43-5

| ATC_prefix = none

| ATC_suffix =

| PubChem = 22031

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = K97CJK0FXR

| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}

| ChemSpiderID = 20703

| synonyms = Phenpentermine; α,β-Dimethylamphetamine; β-Methylphentermine

| IUPAC_name = 2-methyl-3-phenylbutan-2-amine

| C=11 | H=17 | N=1

| SMILES = CC(C1=CC=CC=C1)C(C)(C)N

| StdInChI_Ref = {{stdinchicite|changed|chemspider}}

| StdInChI = 1S/C11H17N/c1-9(11(2,3)12)10-7-5-4-6-8-10/h4-9H,12H2,1-3H3

| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}

| StdInChIKey = UMWAUEZOGHNSCH-UHFFFAOYSA-N

}}

Pentorex, also known as phenpentermine or α,β-dimethylamphetamine and sold under the brand name Modatrop, is a stimulant drug of the amphetamine family related to phentermine (α-methylamphetamine) which is used as an anorectic to assist with weight loss.{{cite journal | vauthors = Behrendt WA, Deininger R | language = German | journal = Arzneimittel-Forschung | volume = 13 | issue = 8 | pages = 711–6 | date = August 1963 | pmid = 14090434 | title = On the Pharmacology of 2-Phenyl-3-Methyl-3-Butylamine, A Substance with Anorexic Action }}{{cite journal | vauthors = Opitz K, Kemper F, Loeser A | title = [Comparative study of the anorexigenic potency of some appetite depressants] | language = German | journal = Arzneimittel-Forschung | volume = 15 | issue = 3 | pages = 278–81 | date = March 1965 | pmid = 5897218 }} It also acts as a diuretic.{{cite journal | vauthors = Opitz K | language = German | journal = Klinische Wochenschrift | volume = 43 | issue = 4 | pages = 225–7 | date = February 1965 | pmid = 14265209 | doi = 10.1007/BF02350860 | title = Natriuretisch-diuretische Wirkung von appetithemmenden Amphetamin-Derivaten | s2cid = 46237660 }} Pentorex was developed by Nordmark in the 1960s.{{ cite patent | country = GB | status = patent | number = 995063 | title = A Substituted Butylamine and Salts thereof | assign1 = Nordmark | gdate = 1965-06-10 }}

It is a derivative of 2-phenyl-3-aminobutane (β-methylamphetamine).