permease
{{Short description|Class of proteins allowing diffusion of molecules in or out of a cell}}
The permeases are membrane transport proteins, a class of multipass transmembrane proteins that allow the diffusion of a specific molecule in or out of the cell in the direction of a concentration gradient, a form of facilitated diffusion. {{Cite web|url=http://www.ks.uiuc.edu/Research/lacY/|title = Substrate Transport in Lactose Permease}}
The permease binding is the first step of translocation. LacY protein from Escherichia coli is an example of a permease.{{Cite book|title=Fundamental laboratory approaches for biochemistry and biotechnology|last1=J.|first1=Ninfa, Alexander|last2=P.|first2=Ballou, David|date=2004|publisher=Wiley|isbn=1891786008|oclc=633862582}}
See also
It was originally discovered in the 1930s by Joy Adames {{Citation needed|date=March 2025|reason=Typo? I can't find any reference for this and thought Permease was connected to Jacques Monod.}}. It is a transporter protein that helps in various aspects of cellular life including DNA replication, translation of RNA, and diffusion.
A permease (porter) is a protein or protein complex that catalyzes a vectorial reaction, irrespective of whether or not it also catalyzes a chemical or electron transfer reaction that drives the vectorial process.
References
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