persistent aura without infarction

{{Infobox medical condition (new)

| name =

| synonym =

| image =

| image_size =

| alt =

| caption =

| pronounce =

| specialty = Neurology, Neuro-ophthalmology

| symptoms = Prolonged aura in vision, Visual snow

| complications =

| onset =

| duration = Long-term

| types =

| causes = Unknown

| risks = Migraine sufferer

| diagnosis =

| differential = Scintillating scotoma, Visual snow

| prevention =

| treatment =

| medication =

| prognosis =

| frequency =

| deaths =

}}

Persistent aura without infarction (PAWOI) is a rare and seemingly benign condition, first described in case reports in 1982 as "prolonged/persistent migraine aura status",{{cite journal|last1=Haas|first1=David C.|title=Prolonged migraine aura status|journal=Annals of Neurology|date=February 1982|volume=11|issue=2|pages=197–9|doi=10.1002/ana.410110217|pmid=7073253|s2cid=73205218}} and in 2000 as "migraine aura status", that is not yet fully understood. PAWOI is said to possibly be a factor involved in a variety of neurological symptoms, including visual snow, loss of vision, increased afterimages, tinnitus, and others. The pathogenesis of PAWOI is unknown. It is not clear which medical examinations are useful in diagnosing PAWOI. At present, PAWOI is usually diagnosed solely based on the patient's current and past symptoms. It is possible that an "overactive brain" or a chemical imbalance underlies the disorder. Various medications have been tried as treatment, notably acetazolamide,{{cite journal|last1=Haan|first1=J|last2=Sluis|first2=P|last3=Sluis|first3=LH|last4=Ferrari|first4=MD|title=Acetazolamide treatment for migraine aura status|journal=Neurology|date=28 November 2000|volume=55|issue=10|pages=1588–9|doi=10.1212/WNL.55.10.1588|pmid=11094126|s2cid=44314478}} valproate,{{cite journal|last1=Rothrock|first1=JF|title=Successful treatment of persistent migraine aura with divalproex sodium|journal=Neurology|date=January 1997|volume=48|issue=1|pages=261–2|doi=10.1212/WNL.48.1.261|pmid=9008529|s2cid=44580050}} lamotrigine,{{cite journal|last1=Chen|first1=WT|last2=Fuh|first2=JL|last3=Lu|first3=SR|last4=Wang|first4=SJ|title=Persistent migrainous visual phenomena might be responsive to lamotrigine|journal=Headache|date=September 2001|volume=41|issue=8|pages=823–5|doi=10.1046/j.1526-4610.2001.01150.x|pmid=11576209|doi-access=|s2cid=20313330 }} topiramate, and furosemide.{{cite journal|last1=Rozen|first1=Todd D.|title=Treatment of a prolonged migrainous aura with intravenous furosemide|journal=Neurology|date=12 September 2000|volume=55|issue=5|pages=732–3|doi=10.1212/WNL.55.5.732|pmid=10980751|s2cid=23474035}}

{{clear}}