phorate
{{Chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 445856103
| ImageFile = Phorate.svg
| ImageSize = 200px
| PIN = O,O-Diethyl S-[(ethylsulfanyl)methyl] phosphorodithioate
| OtherNames = Thimet (trademark)
3911 (trademark)
|Section1={{Chembox Identifiers
| CASNo = 298-02-2
| CASNo_Ref = {{cascite|correct|CAS}}
| PubChem = 4790
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 4626
| ChEBI_Ref = {{ebicite|changed|EBI}}
| ChEBI = 38764
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 510014
| SMILES = S=P(OCC)(SCSCC)OCC
| InChI = 1/C7H17O2PS3/c1-4-8-10(11,9-5-2)13-7-12-6-3/h4-7H2,1-3H3
| InChIKey = BULVZWIRKLYCBC-UHFFFAOYAA
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C7H17O2PS3/c1-4-8-10(11,9-5-2)13-7-12-6-3/h4-7H2,1-3H3
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 3W54X3W9IV
| StdInChIKey = BULVZWIRKLYCBC-UHFFFAOYSA-N
}}
|Section2={{Chembox Properties
| C=7 | H=17 | O=2 | P=1 | S=3
| Appearance = Colorless liquid
| Density = 1.16 g/mL
| MeltingPtF = -45
| BoilingPt = 118-120°C (2.0 mm Hg)Farm Chemicals Handbook, Meister Publishing Co., Willoughby, OH (1991)
| VaporPressure = 0.0008 mmHg (20°C)
}}
|Section3={{Chembox Hazards
| MainHazards =
| FlashPtF = 320
| AutoignitionPt =
| PEL = none{{PGCH|0502}}
| REL = TWA 0.05 mg/m3 ST 0.2 mg/m3 [skin]
}}
}}
Phorate is an organophosphate used as an insecticide and acaricide.
Overview
At normal conditions, it is a pale yellow mobile liquid poorly soluble in water but readily soluble in organic solvents. It is relatively stable and hydrolyses only at very acidic or basic conditions. It is very toxic both for target organisms and for mammals including humans. It inhibits acetylcholinesterase and butyrylcholinesterase.{{Cite web |url=http://www.inchem.org/documents/pds/pds/pest75_e.htm |title=Data sheets on pesticides No. 75 – Phorate |access-date=2011-07-31 |archive-url=https://web.archive.org/web/20140702015027/http://inchem.org/documents/pds/pds/pest75_e.htm |archive-date=2014-07-02 |url-status=dead }}
Phorate is most commonly applied in granular form. It is non-biocumulative and has no residual action. But some metabolites may persist in soil. It also damages some seeds.
Toxicity
References
External links
- {{PPDB|519}}
{{Insecticides}}
{{Acetylcholine metabolism and transport modulators}}
Category:Acetylcholinesterase inhibitors
Category:Organophosphate insecticides