phosphinothricin acetyltransferase

{{Infobox enzyme

| Name = Phosphinothricin acetyltransferase

| EC_number = 2.3.1.183

| CAS_number =

| GO_code =

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Phosphinothricin acetyltransferase ({{EC number|2.3.1.183}}, PAT, PPT acetyltransferase, Pt-N-acetyltransferase, ac-Pt) is an enzyme with systematic name acetyl-CoA:phosphinothricin N-acetyltransferase.{{cite journal | vauthors = Botterman J, Gosselé V, Thoen C, Lauwereys M | title = Characterization of phosphinothricin acetyltransferase and C-terminal enzymatically active fusion proteins | journal = Gene | volume = 102 | issue = 1 | pages = 33–7 | date = June 1991 | pmid = 1864506 | doi = 10.1016/0378-1119(91)90534-i }}{{cite journal | vauthors = Droge-Laser W, Siemeling U, Puhler A, Broer I | title = The Metabolites of the Herbicide L-Phosphinothricin (Glufosinate) (Identification, Stability, and Mobility in Transgenic, Herbicide-Resistant, and Untransformed Plants) | journal = Plant Physiology | volume = 105 | issue = 1 | pages = 159–166 | date = May 1994 | pmid = 12232195 | pmc = 159341 | doi = 10.1104/pp.105.1.159 }} This enzyme catalyses the following chemical reaction

: acetyl-CoA + phosphinothricin $\backslash rightleftharpoons$ CoA + N-acetylphosphinothricin

The substrate phosphinothricin is used as a nonselective herbicide and is a potent inhibitor of EC 6.3.1.2.

File:Acetyl-CoA phosphinothricin N-acetyltransferase.png