phosphomevalonate kinase

{{cs1 config|name-list-style=vanc}}

{{Short description|Protein-coding gene in the species Homo sapiens}}

{{Infobox_gene}}

{{Infobox enzyme

| Name = Phosphomevalonate kinase

| EC_number = 2.7.4.2

| CAS_number = 9026-46-4

| GO_code =

| image =

| width =

| caption =

}}

{{infobox protein

|Name= Phosphomevalonate kinase

|caption=

|image=

|width=

|HGNCid=9141

|Symbol=PMVK

|AltSymbols=

|EntrezGene=10654

|OMIM=607622

|RefSeq=NM_006556

|UniProt=Q15126

|PDB=

|ECnumber=2.7.4.2

|Chromosome=1

|Arm=p

|Band=13

|LocusSupplementaryData=-q23

}}

Phosphomevalonate kinase is an enzyme ({{EC number|2.7.4.2}}) in the mevalonate pathway{{cite journal | vauthors = Bloch K, Chaykin S, Phillips AH, De Waard A | title = Mevalonic acid pyrophosphate and isopentenylpyrophosphate | journal = The Journal of Biological Chemistry | volume = 234 | pages = 2595–604 | date = October 1959 | issue = 10 | doi = 10.1016/S0021-9258(18)69744-3 | pmid = 13801508 | doi-access = free }}{{cite journal | vauthors = Henning U, Moslein EM, Lynen F | title = Biosynthesis of terpenes. V. Formation of 5-pyrophosphomevalonic acid by phosphomevalonic kinase | journal = Archives of Biochemistry and Biophysics | volume = 83 | issue = 1 | pages = 259–67 | date = July 1959 | pmid = 13662013 | doi = 10.1016/0003-9861(59)90031-1 }}{{cite journal | vauthors = Levy HR, Popjak G | title = Studies on the biosynthesis of cholesterol. 10. Mevalonic kinase from liver | journal = The Biochemical Journal | volume = 75 | pages = 417–28 | date = June 1960 | issue = 3 | pmid = 14416398 | pmc = 1204488 | doi = 10.1042/bj0750417 }} that in humans is encoded by the PMVK gene.

Image:Mevalonate_pathway.png]]