platelet-activating factor receptor

Agonists

• Platelet activating factor

Antagonists

• Apafant (WEB-2086)
• Israpafant (Y-24180)
• Lexipafant
• Rupatadine

{{refbegin | 2}}

• {{cite journal | author=Shukla SD |title=Platelet-activating factor receptor and signal transduction mechanisms. |journal=FASEB J. |volume=6 |issue= 6 |pages= 2296–301 |year= 1992 |pmid= 1312046 |doi= 10.1096/fasebj.6.6.1312046|doi-access=free |s2cid=6000303 }}
• {{cite journal |vauthors=Sugimoto T, Tsuchimochi H, McGregor CG, etal |title=Molecular cloning and characterization of the platelet-activating factor receptor gene expressed in the human heart. |journal=Biochem. Biophys. Res. Commun. |volume=189 |issue= 2 |pages= 617–24 |year= 1993 |pmid= 1281995 |doi=10.1016/0006-291X(92)92245-S }}
• {{cite journal |vauthors=Seyfried CE, Schweickart VL, Godiska R, Gray PW |title=The human platelet-activating factor receptor gene (PTAFR) contains no introns and maps to chromosome 1. |journal=Genomics |volume=13 |issue= 3 |pages= 832–4 |year= 1992 |pmid= 1322356 |doi=10.1016/0888-7543(92)90162-L }}
• {{cite journal |vauthors=Kunz D, Gerard NP, Gerard C |title=The human leukocyte platelet-activating factor receptor. cDNA cloning, cell surface expression, and construction of a novel epitope-bearing analog. |journal=J. Biol. Chem. |volume=267 |issue= 13 |pages= 9101–6 |year= 1992 |doi=10.1016/S0021-9258(19)50394-5 |pmid= 1374385 |doi-access=free }}
• {{cite journal |vauthors=Ye RD, Prossnitz ER, Zou AH, Cochrane CG |title=Characterization of a human cDNA that encodes a functional receptor for platelet activating factor. |journal=Biochem. Biophys. Res. Commun. |volume=180 |issue= 1 |pages= 105–11 |year= 1991 |pmid= 1656963 |doi=10.1016/S0006-291X(05)81261-6 }}
• {{cite journal |vauthors=Nakamura M, Honda Z, Izumi T, etal |title=Molecular cloning and expression of platelet-activating factor receptor from human leukocytes. |journal=J. Biol. Chem. |volume=266 |issue= 30 |pages= 20400–5 |year= 1991 |doi=10.1016/S0021-9258(18)54936-X |pmid= 1657923 |doi-access=free }}
• {{cite book |vauthors=Haslam RJ, Williams KA, Davidson MM |title=Mechanisms of Stimulus—Response Coupling in Platelets |chapter=Receptor-Effector Coupling in Platelets: Roles of Guanine Nucleotides |volume=192 |pages= 265–80 |pmid= 3010668 |doi= 10.1007/978-1-4615-9442-0_19 |series=Advances in Experimental Medicine and Biology |date=1985 |isbn=978-1-4615-9444-4 }}
• {{cite journal | author=Valone FH |title=Isolation of a platelet membrane protein which binds the platelet-activating factor 1-0-hexadecyl-2-acetyl-SN-glycero-3-phosphorylcholine. |journal=Immunology |volume=52 |issue= 1 |pages= 169–74 |year= 1984 |pmid= 6325330 | pmc=1454573 }}
• {{cite journal |vauthors=Cundell DR, Gerard NP, Gerard C, etal |title=Streptococcus pneumoniae anchor to activated human cells by the receptor for platelet-activating factor. |journal=Nature |volume=377 |issue= 6548 |pages= 435–8 |year= 1995 |pmid= 7566121 |doi= 10.1038/377435a0 |bibcode=1995Natur.377..435C |s2cid=4318257 }}
• {{cite journal |vauthors=Izumi T, Kishimoto S, Takano T, etal |title=Expression of human platelet-activating factor receptor gene in EoL-1 cells following butyrate-induced differentiation. | series=305 |journal=Biochem. J. |volume=( Pt 3) |issue= 3|pages= 829–35 |year= 1995 |pmid= 7848283 |doi= 10.1042/bj3050829| pmc=1136334 }}
• {{cite journal |vauthors=Bito H, Honda Z, Nakamura M, Shimizu T |title=Cloning, expression and tissue distribution of rat platelet-activating-factor-receptor cDNA. |journal=Eur. J. Biochem. |volume=221 |issue= 1 |pages= 211–8 |year= 1994 |pmid= 8168510 |doi=10.1111/j.1432-1033.1994.tb18731.x |doi-access=free }}
• {{cite journal |vauthors=Chase PB, Halonen M, Regan JW |title=Cloning of a human platelet-activating factor receptor gene: evidence for an intron in the 5'-untranslated region. |journal=Am. J. Respir. Cell Mol. Biol. |volume=8 |issue= 3 |pages= 240–4 |year= 1993 |pmid= 8383507 |doi= 10.1165/ajrcmb/8.3.240}}
• {{cite journal |vauthors=Mutoh H, Bito H, Minami M, etal |title=Two different promoters direct expression of two distinct forms of mRNAs of human platelet-activating factor receptor. |journal=FEBS Lett. |volume=322 |issue= 2 |pages= 129–34 |year= 1993 |pmid= 8387031 |doi=10.1016/0014-5793(93)81552-B |s2cid=44640249 |doi-access=free }}
• {{cite journal |vauthors=Nakamura M, Honda Z, Matsumoto T, etal |title=Isolation and properties of platelet-activating factor receptor cDNAs. |journal=Journal of Lipid Mediators |volume=6 |issue= 1–3 |pages= 163–8 |year= 1993 |pmid= 8395240 }}
• {{cite journal |vauthors=Kishimoto S, Shimadzu W, Izumi T, etal |title=Regulation by IL-5 of expression of functional platelet-activating factor receptors on human eosinophils. |journal=J. Immunol. |volume=157 |issue= 9 |pages= 4126–32 |year= 1996 |doi=10.4049/jimmunol.157.9.4126 |pmid= 8892648 |doi-access=free }}
• {{cite journal |vauthors=Chase PB, Yang JM, Thompson FH, etal |title=Regional mapping of the human platelet-activating factor receptor gene (PTAFR) to 1p35→p34.3 by fluorescence in situ hybridization. |journal=Cytogenet. Cell Genet. |volume=72 |issue= 2–3 |pages= 205–7 |year= 1997 |pmid= 8978777 |doi=10.1159/000134190 }}
• {{cite journal |vauthors=Le Gouill C, Parent JL, Rola-Pleszczynski M, Stanková J |title=Role of the Cys90, Cys95 and Cys173 residues in the structure and function of the human platelet-activating factor receptor. |journal=FEBS Lett. |volume=402 |issue= 2–3 |pages= 203–8 |year= 1997 |pmid= 9037196 |doi=10.1016/S0014-5793(96)01531-1 |s2cid=21074692 |doi-access=free }}
• {{cite journal |vauthors=Ahmed A, Dearn S, Shams M, etal |title=Localization, quantification, and activation of platelet-activating factor receptor in human endometrium during the menstrual cycle: PAF stimulates NO, VEGF, and FAKpp125. |journal=FASEB J. |volume=12 |issue= 10 |pages= 831–43 |year= 1998 |pmid= 9657523 |doi= 10.1096/fasebj.12.10.831|doi-access=free |s2cid=17474972 }}
• {{cite journal |vauthors=Cargill M, Altshuler D, Ireland J, etal |title=Characterization of single-nucleotide polymorphisms in coding regions of human genes. |journal=Nat. Genet. |volume=22 |issue= 3 |pages= 231–8 |year= 1999 |pmid= 10391209 |doi= 10.1038/10290 |s2cid=195213008 }}

{{refend}}

• {{cite web | url = http://www.iuphar-db.org/GPCR/ChapterMenuForward?chapterID=1348 | title = Platelet-Activating Factor Receptor | work = IUPHAR Database of Receptors and Ion Channels | publisher = International Union of Basic and Clinical Pharmacology | access-date = 2007-10-25 | archive-date = 2016-03-03 | archive-url = https://web.archive.org/web/20160303205650/http://www.iuphar-db.org/GPCR/ChapterMenuForward?chapterID=1348 | url-status = dead }}
• {{MeshName|platelet+activating+factor+receptor}}

{{NLM content}}

{{G protein-coupled receptors}}

{{PAF signaling}}

Category:G protein-coupled receptors

{{transmembranereceptor-stub}}