polar T3 syndrome

{{Short description|Low hormone levels in polar explorers}}

{{DISPLAYTITLE:Polar T₃ syndrome}}

Polar T₃ syndrome is a condition found in polar explorers, caused by a decrease in levels of the thyroid hormone T₃.{{cite journal | vauthors = Reed HL, Silverman ED, Shakir KM, Dons R, Burman KD, O'Brian JT | title = Changes in serum triiodothyronine (T₃) kinetics after prolonged Antarctic residence: the polar T₃ syndrome | journal = The Journal of Clinical Endocrinology and Metabolism | volume = 70 | issue = 4 | pages = 965–974 | date = April 1990 | pmid = 2318952 | doi = 10.1210/jcem-70-4-965 }}{{cite journal | vauthors = Palinkas LA, Suedfeld P | title = Psychological effects of polar expeditions | journal = Lancet | volume = 371 | issue = 9607 | pages = 153–163 | date = January 2008 | pmid = 17655924 | doi = 10.1016/S0140-6736(07)61056-3 | s2cid = 9601133 }} Its effects include forgetfulness, cognitive impairment and mood disturbances. It can exhibit itself in a fugue state known as the Antarctic stare.{{cite web|title=Association between the Polar T₃ Syndrome and the Winter-Over Syndrome in Antarctica|url=https://www.nsf.gov/pubs/1999/nsf98106/98106htm/nsf98106h2.html|vauthors=Palinkas LA, Reed HL, Do NV |publisher=Antarctic Journal of the United States Review 1997|year=1997|access-date=2011-11-04}}{{cite web|title=Treating the Antarctic blues|url=https://spacenews.com/treating-the-antarctic-blues/|author=Emily Stone|date=November 9, 2004}}{{cite web|title=Polar T₃ Disorder|url=https://www.nhm.ac.uk/nature-online/earth/antarctica/blog-archive/?p=185|publisher=Natural History Museum|date=17 April 2008}}

Effects of polar environment conditions (long time coldness{{Cite journal |last1=Nikanorova |first1=Alena |last2=Barashkov |first2=Nikolay |last3=Pshennikova |first3=Vera |last4=Teryutin |first4=Fedor |last5=Nakhodkin |first5=Sergey |last6=Solovyev |first6=Aisen |last7=Romanov |first7=Georgii |last8=Burtseva |first8=Tatiana |last9=Fedorova |first9=Sardana |date=2023-09-13 |title=A Systematic Review and Meta-Analysis of Free Triiodothyronine (FT3) Levels in Humans Depending on Seasonal Air Temperature Changes: Is the Variation in FT3 Levels Related to Nonshivering Thermogenesis? |journal=International Journal of Molecular Sciences |volume=24 |issue=18 |pages=14052 |doi=10.3390/ijms241814052 |doi-access=free |pmid=37762355 |issn=1422-0067|pmc=10531421 }} or bioactive factors{{Citation |last1=Besharati |first1=Mohammad Reza |title=A Hypothesis on the Etiology of Polar T3 Syndrome and Related Polar Syndromes: The Role of Atmospheric /Oceanic Iodine in Human Hormonal Cycles in Polar Regions |date=2025-05-06 |url=https://zenodo.org/doi/10.5281/zenodo.15347489 |access-date=2025-05-15 |language=en |doi=10.5281/ZENODO.15347489 |last2=Izadi |first2=Mohammad |last3=Talebpour |first3=Alireza |last4=Jafari |first4=Nafiseh}}) are proposed as hypothetical causes of this syndrome.

It is regarded as one of the contributory causes of winter-over syndrome.