polythiazide
{{Short description|Chemical compound}}
{{Drugbox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 376114224
| IUPAC_name = 6-chloro-2-methyl-3-{[(2,2,2-trifluoroethyl)thio]methyl}-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
| image = Polythiazide.svg
| width = 250
| image2 = Polythiazide molecule spacefill.png
| alt2 = Space-filling model of the polythiazide molecule
| tradename =
| Drugs.com = {{drugs.com|CONS|polythiazide}}
| MedlinePlus = a601101
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| IUPHAR_ligand = 7274
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 346-18-9
| ATC_prefix = C03
| ATC_suffix = AA05
| PubChem = 4870
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank =
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 4704
| UNII_Ref = {{fdacite|changed|FDA}}
| UNII = 36780APV5N
| KEGG_Ref = {{keggcite|changed|kegg}}
| KEGG = D00657
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 1587
| C=11 | H=13 | Cl=1 | F=3 | N=3 | O=4 | S=3
}}
Polythiazide is a thiazide diuretic.{{cite journal | vauthors = O'Brien ET, MacKinnon J | title = Propranolol and polythiazide in treatment of hypertension | journal = British Heart Journal | volume = 34 | issue = 10 | pages = 1042–4 | date = October 1972 | pmid = 5086971 | pmc = 458544 | doi = 10.1136/hrt.34.10.1042 }}{{cite journal | vauthors = Monroy A, Plata C, Hebert SC, Gamba G | title = Characterization of the thiazide-sensitive Na(+)-Cl(-) cotransporter: a new model for ions and diuretics interaction | journal = American Journal of Physiology. Renal Physiology | volume = 279 | issue = 1 | pages = F161-9 | date = July 2000 | pmid = 10894798 | doi = 10.1152/ajprenal.2000.279.1.f161 }}
References
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{{Symporter inhibitors}}
{{Diuretics}}
Category:Carbonic anhydrase inhibitors
Category:Trifluoromethyl compounds
{{cardiovascular-drug-stub}}