polythiazide

{{Short description|Chemical compound}}

{{Drugbox

| Verifiedfields = changed

| Watchedfields = changed

| verifiedrevid = 376114224

| IUPAC_name = 6-chloro-2-methyl-3-{[(2,2,2-trifluoroethyl)thio]methyl}-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide

| image = Polythiazide.svg

| width = 250

| image2 = Polythiazide molecule spacefill.png

| alt2 = Space-filling model of the polythiazide molecule

| tradename =

| Drugs.com = {{drugs.com|CONS|polythiazide}}

| MedlinePlus = a601101

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| IUPHAR_ligand = 7274

| CAS_number_Ref = {{cascite|correct|??}}

| CAS_number = 346-18-9

| ATC_prefix = C03

| ATC_suffix = AA05

| PubChem = 4870

| DrugBank_Ref = {{drugbankcite|correct|drugbank}}

| DrugBank =

| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}

| ChemSpiderID = 4704

| UNII_Ref = {{fdacite|changed|FDA}}

| UNII = 36780APV5N

| KEGG_Ref = {{keggcite|changed|kegg}}

| KEGG = D00657

| ChEMBL_Ref = {{ebicite|changed|EBI}}

| ChEMBL = 1587

| C=11 | H=13 | Cl=1 | F=3 | N=3 | O=4 | S=3

}}

Polythiazide is a thiazide diuretic.{{cite journal | vauthors = O'Brien ET, MacKinnon J | title = Propranolol and polythiazide in treatment of hypertension | journal = British Heart Journal | volume = 34 | issue = 10 | pages = 1042–4 | date = October 1972 | pmid = 5086971 | pmc = 458544 | doi = 10.1136/hrt.34.10.1042 }}{{cite journal | vauthors = Monroy A, Plata C, Hebert SC, Gamba G | title = Characterization of the thiazide-sensitive Na(+)-Cl(-) cotransporter: a new model for ions and diuretics interaction | journal = American Journal of Physiology. Renal Physiology | volume = 279 | issue = 1 | pages = F161-9 | date = July 2000 | pmid = 10894798 | doi = 10.1152/ajprenal.2000.279.1.f161 }}

References