pranidipine

{{Short description|Antihypertensive drug of the calcium channel blocker class}}

{{Refimprove|date=February 2013}}

{{chembox

| Verifiedfields = changed

| Watchedfields = changed

| verifiedrevid = 444299907

| ImageFile=Pranidipine structure.svg

| ImageSize=

| PIN=Methyl (2E)-3-phenylprop-2-en-1-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

| OtherNames=2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid O⁵-methyl O³-[(E)-3-phenylprop-2-enyl] ester

|Section1={{Chembox Identifiers

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = 9DES9QVH58

| CASNo_Ref = {{cascite|correct|??}}

| CASNo=99522-79-9

| PubChem=6436048

| ChEMBL_Ref = {{ebicite|changed|EBI}}

| ChEMBL = 1096842

| SMILES=CC1=C(C(C(=C(N1)C)C(=O)OCC=CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC

| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}

| ChemSpiderID = 4940726

| InChI = 1/C25H24N2O6/c1-16-21(24(28)32-3)23(19-12-7-13-20(15-19)27(30)31)22(17(2)26-16)25(29)33-14-8-11-18-9-5-4-6-10-18/h4-13,15,23,26H,14H2,1-3H3/b11-8+

| InChIKey = XTFPDGZNWTZCMF-DHZHZOJOBA

| StdInChI_Ref = {{stdinchicite|changed|chemspider}}

| StdInChI = 1S/C25H24N2O6/c1-16-21(24(28)32-3)23(19-12-7-13-20(15-19)27(30)31)22(17(2)26-16)25(29)33-14-8-11-18-9-5-4-6-10-18/h4-13,15,23,26H,14H2,1-3H3/b11-8+

| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}

| StdInChIKey = XTFPDGZNWTZCMF-DHZHZOJOSA-N

| RTECS =

| MeSHName = C048161

}}

|Section2={{Chembox Properties

| Formula=C₂₅H₂₄N₂O₆

| MolarMass=448.46786

| Appearance=

| Density=

| MeltingPt=

| BoilingPt=

| Solubility=

}}

|Section3={{Chembox Hazards

| MainHazards=

| FlashPt=

| AutoignitionPt =

}}

}}

Pranidipine is a calcium channel blocker. It is a long acting calcium channel antagonist of the dihydropyridine group.{{ cite journal |author1=Jin Yang |author2=Keisuke Fukuo |author3=Shigeto Morimoto |author4=Tadaaki Niinobu |author5=Toshimitsu Suhara |author6=Toshio Ogihara | title = Pranidipine Enhances the Action of Nitric Oxide Released From Endothelial Cells | journal = Hypertension | year = 2000 | volume = 35 |issue=1 Pt 1 | pages = 82–85 | doi=10.1161/01.hyp.35.1.82|pmid=10642279 | doi-access=free }}