rafoxanide

{{chembox

| Verifiedfields = changed

| Watchedfields = changed

| verifiedrevid = 444411143

| ImageFile = Rafoxanide.svg

| ImageSize = 250

| PIN = N-[3-Chloro-4-(4-chlorophenoxy)phenyl]-2-hydroxy-3,5-diiodobenzamide

| OtherNames = Rafoxanid, raphoxanide

| Section1 = {{Chembox Identifiers

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = 22F4FLA7DH

| CASNo_Ref = {{cascite|correct|??}}

| CASNo = 22662-39-1

| PubChem = 31475

| ChEBI = 234200

| ChEMBL_Ref = {{ebicite|changed|EBI}}

| ChEMBL = 287542

| EINECS = 245-148-9

| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}

| ChemSpiderID = 29191

| KEGG_Ref = {{keggcite|changed|kegg}}

| KEGG = D05693

| InChI = 1/C19H11Cl2I2NO3/c20-10-1-4-13(5-2-10)27-17-6-3-12(9-15(17)21)24-19(26)14-7-11(22)8-16(23)18(14)25/h1-9,25H,(H,24,26)

| InChIKey = NEMNPWINWMHUMR-UHFFFAOYAP

| StdInChI_Ref = {{stdinchicite|changed|chemspider}}

| StdInChI = 1S/C19H11Cl2I2NO3/c20-10-1-4-13(5-2-10)27-17-6-3-12(9-15(17)21)24-19(26)14-7-11(22)8-16(23)18(14)25/h1-9,25H,(H,24,26)

| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}

| StdInChIKey = NEMNPWINWMHUMR-UHFFFAOYSA-N

| RTECS =

| MeSHName = D011888

| SMILES=C1=CC(=CC=C1OC2=C(C=C(C=C2)NC(=O)C3=CC(=CC(=C3O)I)I)Cl)Cl

}}

| Section2 = {{Chembox Properties

| Formula = C19H11Cl2I2NO3

| MolarMass = 626.01 g/mol

| Appearance = Slight yellowish-brown injectable solution and white oral solution

| Density =

| MeltingPt =

| BoilingPt =

| Solubility = In oily solutes

}}

| Section6 = {{Chembox Pharmacology

| ATCvet = yes

| ATCCode_prefix = P52

| ATCCode_suffix = AG05

}}

| Section7 = {{Chembox Hazards

| MainHazards = Has low safety index (6 times as normal dose)

| FlashPt =

| AutoignitionPt =

}}

}}

Rafoxanide is a salicylanilide used as an anthelmintic.{{cite book |last1=Lanusse |first1=Carlos E. |last2=Alvarez |first2=Luis I. |last3=Virkel |first3=Guillermo L. |editor1-last=Riviere |editor1-first=Jim E. |editor2-last=Papich |editor2-first=Mark G. |title=Veterinary Pharmacology and Therapeutics |date=2018 |publisher=John Wiley & Sons |isbn=9781118855829 |page=1091 |edition=10th |chapter=Chapter 40. Anticestodal and antitrematodal drugs. Rafoxanide}} It is most commonly used in ruminant animals to treat adult liver flukes of the species Fasciola hepatica and Fasciola gigantica.

References