rectilinear scanner
{{Short description|Obsolete radiopharmaceutical imaging device}}
{{Infobox diagnostic
| name = Rectilinear scanner
| image = File:Rectilinear scan and chest X-ray fusion.png|thumb|
| alt =
| caption = Manual image fusion of x-rayed and rectilinear scanned chest
| pronounce =
| purpose =capture emission from radiopharmaceuticals in nuclear medicine.
| test of =
| based on =
| synonyms =
| reference_range =
| calculator =
| DiseasesDB =
| ICD10 =
| ICD9 =
| ICDO =
| MedlinePlus =
| eMedicine =
| MeshID =
| OPS301 =
| LOINC =
}}
A rectilinear scanner is an imaging device, used to capture emission from radiopharmaceuticals in nuclear medicine. The image is created by physically moving a radiation detector over the surface of a radioactive patient. It has become obsolete in medical imaging, largely replaced by the gamma camera since the late 1960s.{{cite journal|last1=Williams|first1=Lawrence E.|title=Anniversary Paper: Nuclear medicine: Fifty years and still counting|journal=Medical Physics|date=12 June 2008|volume=35|issue=7|pages=3020–3029|doi=10.1118/1.2936217|pmid=18697524|doi-access=free|pmc=2673554|bibcode=2008MedPh..35.3020W}}{{cite journal|last1=Blahd|first1=WH|title=Ben Cassen and the development of the rectilinear scanner.|journal=Seminars in Nuclear Medicine|date=July 1996|volume=26|issue=3|pages=165–70|doi=10.1016/s0001-2998(96)80021-3|pmid=8829277}}{{cite book|last1=Feld|first1=Michael|last2=de Roo|first2=Michel|title=History of nuclear medicine in Europe|date=2003|publisher=Schattauer|location=Stuttgart|isbn=9783794522347|page=3|url=https://books.google.com/books?id=MumQU40Pe04C&pg=PA8}}
History
One of the first rectilinear scanners was developed by Benedict Cassen in 1950. Before then hand-held detectors had been used to locate radioactive materials in patients, but the Cassen system (designed for Iodine-131) combined a motor driven photomultiplier tube and printing mechanism.{{cite journal|last1=Hutton|first1=Brian F|title=The contribution of Medical Physics to Nuclear Medicine: looking back - a physicist's perspective|journal=EJNMMI Physics|date=2014|volume=1|issue=1|pages=2|doi=10.1186/2197-7364-1-2|pmid=26501444|pmc=4545618 |doi-access=free }} Subsequent developments improved the detection systems, movement, display and printing of images.{{cite web|last1=McCready|first1=Ralph|title=Early days in the Evolution of Radioisotope Imaging In the UK 1950-1970|url=http://www.bnms.org.uk/~bnms/images/stories/downloads/documents/microsoft_word_-_text_for_the_nukdoctor_web_page..pdf|website=BNMS|access-date=19 February 2017}}{{cite book|last1=McCready|first1=Ralph|title=A History of Radionuclide Studies in the UK|pages=9–18|date=2016|publisher=Springer|location=London|isbn=978-3-319-28623-5|chapter=A History of Nuclear Medicine in the UK|doi=10.1007/978-3-319-28624-2_2|pmid=29787085}}
Components
Cassen's original rectilinear scanner used calcium tungstate (CaWo4) crystal as the radiation detector. Later systems used a Sodium iodide (NaI) scintillator, as in a gamma camera.{{cite book|last1=Hendee|first1=William R|last2=Ritenour|first2=E Russell|title=Medical Imaging Physics, Fourth Edition.|date=2002|publisher=John Wiley & Sons|location=Hoboken, NJ|isbn=9780471461135|page=210|edition=4th}} The detector must be connected by mechanical or electronic means to an output system. This could be a simple light source over photographic film, dot matrix printer, oscilloscope or television screen.{{cite journal|last1=Mayneord|first1=WV|last2=Turner|first2=R C|last3=Newbery|first3=SP|last4=Hodt|first4=HJ|title=A Method of Making Visible the Distribution of Activity in a Source of Ionizing Radiation|journal=Nature|date=3 November 1951|volume=168|issue=4279|pages=762–765|doi=10.1038/168762a0|bibcode=1951Natur.168..762M|s2cid=4204188}}{{cite journal|last1=Dowsett|first1=DJ|last2=Ritchie|first2=DR|title=An off-line computer interface for a rectilinear scanner|journal=Physics in Medicine and Biology|date=1 April 1971|volume=16|issue=2|pages=249–256|doi=10.1088/0031-9155/16/2/307|pmid=5581630|bibcode=1971PMB....16..249D}}{{cite journal|last1=Reese|first1=IC|last2=Mishkin|first2=FS|title=Direct recording on rectilinear scan images on 4x5-in. film.|journal=Journal of Nuclear Medicine|date=October 1976|volume=17|issue=10|pages=937–8|pmid=966063|url=http://jnm.snmjournals.org/content/17/10/937.long}}
Mechanism
The patient is administered with a radioactive pharmaceutical agent, such as radio-iodine which will naturally collect in the thyroid. The detector moves in a raster pattern over studied area of the patient, making a constant count rate. A collimator restricts detection to a small area directly below its position so that by the end of the scan emission from the whole study area has been detected. The output method is designed such that positional and detection information is maintained. For example, when using a light source and film the light is moved in tandem with the detector, and the intensity of light produced increases with an increase in activity, producing dark areas on the film.{{cite news|last1=van Herk|first1=G|title=Nuclear imaging: Advances and trends|url=https://www.iaea.org/sites/default/files/publications/magazines/bulletin/bull28-2/28205882025.pdf|work=IAEA Bulletin|date=1986}}{{cite book|last1=Patton|first1=Dennis D|title=Nuclear Medicine, Ultrasonics, and Thermography|date=1980|publisher=Springer|location=New York|isbn=978-1-4684-3673-0|pages=89–118|chapter=Rectilinear Scanners|doi=10.1007/978-1-4684-3671-6_3}}
Disadvantages include the very long imaging time (several minutes) due to the need to separately cover each target area, unlike a gamma camera which has a much larger field of view, and the motion artefacts this can result in.{{cite book|last1=Cherry|first1=Simon R|last2=Sorenson|first2=James A|last3=Phelps|first3=Michael E|title=Physics in nuclear medicine|url=https://archive.org/details/physicsnuclearme00phds|url-access=limited|date=2012|publisher=Elsevier/Saunders|location=Philadelphia|isbn=978-1-4160-5198-5|pages=[https://archive.org/details/physicsnuclearme00phds/page/n216 195]–208|edition=4th|chapter=The Gamma Camera: Basic Principles|doi=10.1016/B978-1-4160-5198-5.00013-7}}{{cite journal|last1=Gottschalk|first1=A|last2=Harper|first2=PV|last3=Jiminez|first3=FF|last4=Petasnick|first4=JP|title=Quantification of the respiratory motion artifact in radioisotope scanning with the rectilinear focused collimator scanner and the gamma scintillation camera.|journal=Journal of Nuclear Medicine|date=April 1966|volume=7|issue=4|pages=243–51|pmid=5930230|url=http://jnm.snmjournals.org/content/7/4/243.long}}