relapsing–remitting

{{Short description|Medical symptoms which cyclically worsen and improve with time}}

Relapsing–remitting is a medical term referring to a presentation of disease symptoms that become worse over time (relapsing), followed by periods of less severe symptoms that do not completely cease (partial remitting). The term is used to describe a type of multiple sclerosis called relapsing–remitting multiple sclerosis, where unpredictable relapses are followed by remission for months to years.{{Cite journal |last1=Brown |first1=Fraser S. |last2=Glasmacher |first2=Stella A. |last3=Kearns |first3=Patrick K. A. |last4=MacDougall |first4=Niall |last5=Hunt |first5=David |last6=Connick |first6=Peter |last7=Chandran |first7=Siddharthan |date=2020-05-26 |title=Systematic review of prediction models in relapsing remitting multiple sclerosis |journal=PLOS ONE |language=en |volume=15 |issue=5 |pages=e0233575 |doi=10.1371/journal.pone.0233575 |issn=1932-6203 |pmc=7250448 |pmid=32453803|doi-access=free |bibcode=2020PLoSO..1533575B }}

The term is also used to describe palindromic rheumatism in the context of rheumatoid arthritis,{{Cite journal |last1=Mankia |first1=Kulveer |last2=Emery |first2=Paul |date=2019-10-08 |title=Palindromic rheumatism as part of the rheumatoid arthritis continuum |url=http://dx.doi.org/10.1038/s41584-019-0308-5 |journal=Nature Reviews Rheumatology |volume=15 |issue=11 |pages=687–695 |doi=10.1038/s41584-019-0308-5 |pmid=31595059 |s2cid=203912180 |issn=1759-4790}} catatonia,{{Cite journal |last1=Nath |first1=Santanu |last2=Bhoi |first2=Rosali |last3=Mishra |first3=Biswaranjan |last4=Padhy |first4=Susanta |date=September 2021 |title=Does recurrent catatonia manifest in a similar fashion in all the episodes of mood disorder? A case series with literature review |url=http://dx.doi.org/10.1136/gpsych-2021-100494 |journal=General Psychiatry |volume=34 |issue=5 |pages=e100494 |doi=10.1136/gpsych-2021-100494 |pmid=34595400 |pmc=8420649 |issn=2517-729X}}{{Cite journal |last1=Gerra |first1=Maria Lidia |last2=Mutti |first2=Carlotta |last3=Luviè |first3=Lorenzo |last4=Daniel |first4=Benyamin Daniel |last5=Florindo |first5=Irene |last6=Picetti |first6=Edoardo |last7=Parrino |first7=Liborio |last8=Marchesi |first8=Carlo |last9=Zinno |first9=Lucia |date=2022-01-02 |title=Relapsing–remitting psychosis with malignant catatonia: a multidisciplinary challenge |url=http://dx.doi.org/10.1080/13554794.2022.2032185 |journal=Neurocase |volume=28 |issue=1 |pages=126–130 |doi=10.1080/13554794.2022.2032185 |pmid=35176968 |s2cid=246943998 |issn=1355-4794}} lupus,{{Cite journal |last1=Tamirou |first1=Farah |last2=Arnaud |first2=Laurent |last3=Talarico |first3=Rosaria |last4=Scirè |first4=Carlo Alberto |last5=Alexander |first5=Tobias |last6=Amoura |first6=Zahir |last7=Avcin |first7=Tadej |last8=Bortoluzzi |first8=Alessandra |last9=Cervera |first9=Ricard |last10=Conti |first10=Fabrizio |last11=Cornet |first11=Alain |date=January 2019 |title=Systemic lupus erythematosus: state of the art on clinical practice guidelines |journal=RMD Open |language=en |volume=4 |issue=Suppl 1 |pages=e000793 |doi=10.1136/rmdopen-2018-000793 |issn=2056-5933 |pmc=6269635 |pmid=30564454}} mental disorders,{{Cite journal |last1=Bock |first1=Astrid |last2=Huber |first2=Eva |last3=Müller |first3=Steffen |last4=Henkel |first4=Miriam |last5=Sevecke |first5=Kathrin |last6=Schopper |first6=Alexander |last7=Steinmayr-Gensluckner |first7=Maria |last8=Wieser |first8=Elke |last9=Benecke |first9=Cord |date=2019-09-01 |title=Levels of structural integration in adolescents and the relationship to later mental disorders – A longitudinal study |url=http://dx.doi.org/10.1024/1422-4917/a000656 |journal=Zeitschrift für Kinder- und Jugendpsychiatrie und Psychotherapie |volume=47 |issue=5 |pages=400–410 |doi=10.1024/1422-4917/a000656 |pmid=30939974 |s2cid=150523412 |issn=1422-4917}} and experimental autoimmune encephalomyelitis.{{Cite journal |last1=Klaren |first1=Rachel E. |last2=Stasula |first2=Ulana |last3=Steelman |first3=Andrew J. |last4=Hernandez |first4=Jessica |last5=Pence |first5=Brandt D. |last6=Woods |first6=Jeffrey A. |last7=Motl |first7=Robert W. |date=2016-06-17 |title=Effects of exercise in a relapsing-remitting model of experimental autoimmune encephalomyelitis |url=http://dx.doi.org/10.1002/jnr.23783 |journal=Journal of Neuroscience Research |volume=94 |issue=10 |pages=907–914 |doi=10.1002/jnr.23783 |pmid=27312674 |s2cid=35994576 |issn=0360-4012}}