ribosome-nascent chain complex

File:Ribosome-Nascent chain complex.png

Ribosome-nascent chain complex (RNC) refers to the collection of molecules that constitute a ribosome attached to the polypeptide (protein) that it is synthesising. The synthesis of the nascent polypeptide may be stalled by one of several methods. RNCs are produced and purified in laboratories to study the dynamics, biochemistry, folding and interactions of both the ribosome and proteins undergoing synthesis.

References

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{{cite journal | vauthors = Cabrita LD, Dobson CM, Christodoulou J | title = Protein folding on the ribosome | journal = Current Opinion in Structural Biology | volume = 20 | issue = 1 | pages = 33–45 | date = February 2010 | pmid = 20149635 | doi = 10.1016/j.sbi.2010.01.005 }}

{{cite journal | vauthors = Schaffitzel C, Ban N | title = Generation of ribosome nascent chain complexes for structural and functional studies | journal = Journal of Structural Biology | volume = 158 | issue = 3 | pages = 463–71 | date = June 2007 | pmid = 17350284 | doi = 10.1016/j.jsb.2007.01.005 }}

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Category:Protein complexes

Category:Protein biosynthesis