ronidazole

{{distinguish|ornidazole}}

{{Chembox

| ImageFile = Ronidazole Structural Formula V.1.svg

| PIN = (1-Methyl-5-nitro-1H-imidazol-2-yl)methyl carbamate

| OtherNames =

|Section1={{Chembox Identifiers

| CASNo = 7681-76-7

| CASNo_Ref = {{cascite|correct|CAS}}

| PubChem = 5094

| ChemSpiderID = 4915

| ChEMBL = 290299

| UNII = E01R4M1063

| SMILES = O=C(OCc1ncc(n1C)[N+]([O-])=O)N

| InChI = InChI=1S/C6H8N4O4/c1-9-4(3-14-6(7)11)8-2-5(9)10(12)13/h2H,3H2,1H3,(H2,7,11)

}}

|Section2={{Chembox Properties

| C=6 | H=8 | N=4 | O=4

| Appearance =

| Density =

| MeltingPt =

| BoilingPt =

| Solubility =

}}

|Section6={{Chembox Pharmacology

| ATCvet = yes

| ATCCode_prefix = P51

| ATCCode_suffix = CA02

}}

|Section7={{Chembox Hazards

| MainHazards =

| FlashPt =

| AutoignitionPt =

}}

}}

Ronidazole is an antiprotozoal agent used in veterinary medicine for the treatment of histomoniasis and swine dysentery{{Cite journal |last1=Sullivan |first1=T.W. |last2=Grace |first2=O.D. |last3=Aksoy |first3=Ayhan |date=1977-03-01 |title=Influence of Level, Timing and Duration of Ronidazole Water Medication on Histomoniasis in Turkeys1 |journal=Poultry Science |volume=56 |issue=2 |pages=571–576 |doi=10.3382/ps.0560571 |pmid=564505 |issn=0032-5791 |lang=en|doi-access=free }}{{Cite journal |last1=Olson |first1=L. D. |last2=Rodabaugh |first2=D. E. |date=July 1976 |title=Ronidazole in low concentrations in drinking water for treatment and development of immunity to swine dysentery. |url=https://pubmed.ncbi.nlm.nih.gov/937800/ |url-status=live |journal=American Journal of Veterinary Research |volume=37 |issue=7 |pages=763–767 |issn=0002-9645 |pmid=937800 |archive-url=https://web.archive.org/web/20220317164259/https://pubmed.ncbi.nlm.nih.gov/937800/ |archive-date=2022-03-17 |access-date=2022-03-17 |lang=en}} as well as Trichomonas gallinae, hexamitosis, Giardia, and Cochlosoma in all aviary birds and pigeons.{{Cite web |title=Ronidazole |url=https://allbirdproducts.com/products/ronidazole |url-status=live |archive-url=https://web.archive.org/web/20210514042918/https://allbirdproducts.com/products/ronidazole |archive-date=2021-05-14 |access-date=2022-03-17 |website=All Bird Products |language=en}} It may also have use for the treatment of Tritrichomonas foetus infection in cats{{Cite journal |last1=Gunn-Moore |first1=Danielle |last2=Lalor |first2=Stephanie |date=2011-01-01 |title=Treatment of diarrhoea in cats caused by Tritrichomonas foetus |url=https://bvajournals.onlinelibrary.wiley.com/doi/abs/10.1136/vr.d189 |url-status=live |journal=Veterinary Record |volume=168 |issue=2 |pages=56–57 |doi=10.1136/vr.d189 |issn=0042-4900 |pmid=21257565 |s2cid=207041640 |archive-url=https://web.archive.org/web/20220317170142/https://bvajournals.onlinelibrary.wiley.com/doi/abs/10.1136/vr.d189 |archive-date=2022-03-17 |access-date=2022-03-17 |lang=en|url-access=subscription }}{{Cite web |date=December 2009 |title=Tritrichomonas foetus infection in cats and treatment with RONIDAZOLE |url=https://www.ed.ac.uk/files/imports/fileManager/Ronidazole%20treatment%20sheet%20for%20vets%20-%202009.pdf |url-status=live |archive-url=https://archive.today/20220317162531/https://www.ed.ac.uk/files/imports/fileManager/Ronidazole%20treatment%20sheet%20for%20vets%20-%202009.pdf |archive-date=2022-03-17 |access-date=2022-03-17 |website=University of Edinburgh |language=en}}{{Cite journal |last=Davidson |first=Gigi S. |date=December 2006 |title=Ronidazole in the treatment of trichomonad infections in cats. |url=https://pubmed.ncbi.nlm.nih.gov/23974416/ |url-status=live |journal=International Journal of Pharmaceutical Compounding |volume=10 |issue=6 |pages=434–435 |issn=1092-4221 |pmid=23974416 |archive-url=https://web.archive.org/web/20220317163538/https://pubmed.ncbi.nlm.nih.gov/23974416/ |archive-date=2022-03-17 |access-date=2022-03-17 |lang=en}} and for the treatment of Clostridioides difficile infection in humans.{{Cite journal |last1=AbdelKhalek |first1=Ahmed |last2=Seleem |first2=Mohamed N. |date=December 2020 |title=Repurposing the Veterinary Antiprotozoal Drug Ronidazole for the Treatment of Clostridioides difficile Infection |journal=International Journal of Antimicrobial Agents |volume=56 |issue=6 |pages=106188 |doi=10.1016/j.ijantimicag.2020.106188 |issn=1872-7913 |pmc=7704610 |pmid=33045352 |lang=en}}

References