sacubitrilat

{{Short description|Chemical compound}}

{{Infobox drug

| drug_name =

| IUPAC_name = (2R,4S)-5-(4-Biphenylyl)-4-[(3-carboxypropanoyl)amino]-2-methylpentanoic acid

| image = Sacubitrilat skeletal.svg

| alt =

| caption =

| pronounce =

| tradename =

| Drugs.com =

| MedlinePlus =

| pregnancy_AU =

| pregnancy_AU_comment =

| pregnancy_US =

| pregnancy_category=

| legal_AU =

| legal_AU_comment =

| legal_CA =

| legal_NZ =

| legal_UK =

| legal_US =

| legal_UN =

| legal_status =

| routes_of_administration =

| bioavailability =

| protein_bound =

| metabolism =

| metabolites =

| onset =

| elimination_half-life =

| duration_of_action =

| excretion =

| CAS_number = 149709-44-4

| ATCvet =

| ATC_prefix = none

| ATC_suffix =

| PubChem = 10430040

| DrugBank =

| UNII = SPI5PBF81S

| ChEMBL = 417007

| ChemSpiderID = 8605468

| synonyms = LBQ657

| PDB_ligand = 6LD

| C=22 | H=25 | N=1 | O=5

| smiles = C[C@H](C[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)O)C(=O)O

| StdInChI=1S/C22H25NO5/c1-15(22(27)28)13-19(23-20(24)11-12-21(25)26)14-16-7-9-18(10-8-16)17-5-3-2-4-6-17/h2-10,15,19H,11-14H2,1H3,(H,23,24)(H,25,26)(H,27,28)/t15-,19+/m1/s1

| StdInChIKey = DOBNVUFHFMVMDB-BEFAXECRSA-N

}}

Sacubitrilat (INN; or LBQ657) is the active metabolite of the antihypertensive drug sacubitril, which is used in the treatment of heart failure.