sulconazole
{{Short description|Chemical compound}}
{{Drugbox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 470472797
| IUPAC_name = 1-(2-{[(4-Chlorophenyl)methyl]sulfanyl}-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole
| image = Sulconazole.svg
| tradename = Exelderm
| Drugs.com = {{drugs.com|monograph|exelderm}}
| MedlinePlus = a698018
| pregnancy_category =
| legal_status =
| routes_of_administration = Topical
| bioavailability =
| metabolism =
| excretion =
| CAS_number_Ref = {{cascite|changed|??}}
| CAS_number = 61318-90-9
| ATC_prefix = D01
| ATC_suffix = AC09
| PubChem = 5318
| DrugBank= DB06820
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 5127
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 5D9HAA5Q5S
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D08535
| ChEBI_Ref = {{ebicite|changed|EBI}}
| ChEBI = 9325
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 1221
| C=18 | H=15 | Cl=3 | N=2 | S=1
| smiles = Clc1ccc(c(Cl)c1)C(SCc2ccc(Cl)cc2)Cn3ccnc3
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C18H15Cl3N2S/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21/h1-9,12,18H,10-11H2
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = AFNXATANNDIXLG-UHFFFAOYSA-N
}}
Sulconazole (trade name Exelderm) is an antifungal medication of the imidazole class. It is available as a cream or solution to treat skin infections such as athlete's foot, ringworm, jock itch, and tinea versicolor.Drugs.com: [https://www.drugs.com/mtm/sulconazole-topical.html sulconazole topical]{{cite journal | vauthors = Fromtling RA | title = Overview of medically important antifungal azole derivatives | journal = Clinical Microbiology Reviews | volume = 1 | issue = 2 | pages = 187–217 | date = April 1988 | pmid = 3069196 | pmc = 358042 | doi = 10.1128/CMR.1.2.187 }} Although not used commercially for insect control, sulconazole nitrate exhibits a strong anti-feeding effect on the keratin-digesting Australian carpet beetle larvae Anthrenocerus australis.{{cite journal | vauthors = Sunderland MR, Cruickshank RH, Leighs SJ | year = 2014 | title = The efficacy of antifungal azole and antiprotozoal compounds in protection of wool from keratin-digesting insect larvae | journal = Textile Research Journal | volume = 84 | issue = 9| pages = 924–931 | doi=10.1177/0040517513515312| s2cid = 135799368 }}
References
{{reflist}}
{{Antifungals}}
Category:Imidazole antifungals
Category:Lanosterol 14α-demethylase inhibitors
Category:4-Chlorophenyl compounds
{{Antimicrobial-stub}}