sulfamation

In organic chemistry sulfamation is the installation of either of two related functional groups, sulfamic acid (R₂NSO₃H) and sulfamate (R₂NSO₃⁻). Typical methods entail reaction of primary amines with sources of sulfur trioxide such as pyridine-sulfur trioxide:{{cite journal |doi=10.1021/jo01314a033|title=Sulfonylamine-Mediated Sulfamation of Amines. A Mild, High Yield Synthesis of Sulfamic Acid Salts|year=1980|last1=DuBois|first1=Grant E.|last2=Stephenson|first2=Rebecca A.|journal=The Journal of Organic Chemistry|volume=45|issue=26|pages=5371–5373}}

:RNH₂ + SO₃ → RNHSO₃H

Sulfamation can also be effected by treating the amine with the sulfate ester of catechol (C₆H₄O₂SO₂).