sulfamethoxypyridazine
{{Short description|Chemical compound}}
{{refimprove|date=June 2021}}
{{Drugbox
| Verifiedfields = changed
| verifiedrevid = 470473115
| IUPAC_name = 4-amino-N-(6-methoxypyridazin-3-yl)benzenesulfonamide
| image = Sulfamethoxypyridazine.png
| tradename =
| Drugs.com = {{drugs.com|international|sulfamethoxypyridazine}}
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| legal_status =
| routes_of_administration =
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
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| CAS_number_Ref = {{cascite|changed|??}}
| CAS_number = 80-35-3
| ATC_prefix = J01
| ATC_suffix = ED05
| ATC_supplemental = {{ATCvet|J01|EQ15}}
| PubChem = 5330
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank =
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 5139
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = T034E4NS2Z
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D02439
| ChEBI_Ref = {{ebicite|correct|EBI}}
| ChEBI = 102516
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 268869
| C=11 | H=12 | N=4 | O=3 | S=1
| smiles = O=S(=O)(Nc1nnc(OC)cc1)c2ccc(N)cc2
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C11H12N4O3S/c1-18-11-7-6-10(13-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,15)
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = VLYWMPOKSSWJAL-UHFFFAOYSA-N
}}
Sulfamethoxypyridazine is a sulfonamide antibacterial.{{cite journal | vauthors = Boger WP, Gylfe JM, Strickland CS | title = Sulfamethoxypyridazine (Kynex), a new long-acting sulfonamide | journal = Antibiotic Medicine & Clinical Therapy | location = New York, NY | volume = 3 | issue = 6 | pages = 378–87 | date = November 1956 | pmid = 13363378 | doi = | url = }}
It is prescribed for vaginal irritation, and severe acute thrush.
It is also used in the treatment of Dermatitis herpetiformis,{{cite journal | vauthors = Vilanova X, De Moragas JM | title = [Treatment of dermatitis herpetiformis (Duhring) and herpes gestationis with sulfamethoxypyridazine] | language=es| journal = Actas Dermo-sifiliograficas | volume = 50 | issue = | pages = 439–42 | date = October 1959 | pmid = 13842251 | doi = | url = }} where it is an alternative therapy to Dapsone.
Sulfamethoxypyridazine is supplied as 500mg tablets.
References
{{Reflist}}
{{Sulfonamides and trimethoprim}}
Category:Sulfonamide antibiotics
Category:4-Aminophenyl compounds
{{antibiotic-stub}}