systemic administration

Systemic administration is a route of administration of medication, nutrition or other substance into the circulatory system so that the entire body is affected.{{cite book|title=Hunnius Pharmazeutisches Wörterbuch|year=1998|edition=8th|publisher=Walter de Gruyter|language=German|location=Berlin|isbn=3-11-015793-4|page=1477}} Administration can take place via enteral administration (absorption of the drug through the gastrointestinal tract){{cite web|url=http://www.britannica.com/EBchecked/topic/188838/enteral-administration|title=Enteral administration - pharmacology|author=|date=|website=britannica.com|accessdate=19 April 2018}} or parenteral administration (generally injection, infusion, or implantation).{{cite book|title=Hunnius Pharmazeutisches Wörterbuch|year=1998|edition=8th|publisher=Walter de Gruyter|language=German|location=Berlin|isbn=3-11-015793-4|pages=472, 1029}}{{cite book|last1=Mutschler|first1=Ernst|title=Arzneimittelwirkungen|language=German|location=Stuttgart|publisher=Wissenschaftliche Verlagsgesellschaft|year=2013|edition=10|page=8|isbn=978-3-8047-2898-1}}

Contrast with topical administration where the effect is generally local.