tetroxoprim
{{Short description|Chemical compound}}
{{refimprove|date=August 2014}}
{{Drugbox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 408927686
| IUPAC_name = 5-[3,5-Dimethoxy-4-(2-methoxyethoxy)benzyl]pyrimidine-2,4-diamine
| image = Tetroxoprim.svg
| tradename =
| pregnancy_AU =
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| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 53808-87-0
| ATC_prefix = J01
| ATC_suffix = EE06
| ATC_supplemental = (with sulfadiazine)
| PubChem = 65450
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank =
| UNII_Ref = {{fdacite|changed|FDA}}
| UNII = 5R6712AY0K
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D06097
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 32039
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 58910
| chemical_formula =
| C=16 | H=22 | N=4 | O=4
| smiles = COCCOC1=C(C=C(C=C1OC)CC2=CN=C(N=C2N)N)OC
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI = 1S/C16H22N4O4/c1-21-4-5-24-14-12(22-2)7-10(8-13(14)23-3)6-11-9-19-16(18)20-15(11)17/h7-9H,4-6H2,1-3H3,(H4,17,18,19,20)
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
| StdInChIKey = WSWJIZXMAUYHOE-UHFFFAOYSA-N
}}
Tetroxoprim (INN) is a derivative of trimethoprim. It was first described in 1979.{{cite journal |vauthors=Aschhoff HS, Vergin H |title=Tetroxoprim—a new inhibitor of bacterial dihydrofolate reductase |journal=J Antimicrob Chemother |volume=5 |issue=B |pages=19–25 |date=November 1979 |pmid=43863 |doi= 10.1093/jac/5.supplement_b.19}}
Its chemical formula is C=16 | H=22 | N=4 | O=4. {{Cite web|url=https://pubchem.ncbi.nlm.nih.gov/compound/65450|title=Tetroxoprim|website=pubchem.ncbi.nlm.nih.gov}}{{Cite web|url=https://www.sciencedirect.com/topics/nursing-and-health-professions/tetroxoprim|title=Tetroxoprim - an overview | ScienceDirect Topics|website=www.sciencedirect.com}}
References
{{Reflist}}
{{Sulfonamides and trimethoprim}}
Category:Bacterial dihydrofolate reductase inhibitors
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