tetroxoprim

{{Short description|Chemical compound}}

{{refimprove|date=August 2014}}

{{Drugbox

| Verifiedfields = changed

| Watchedfields = changed

| verifiedrevid = 408927686

| IUPAC_name = 5-[3,5-Dimethoxy-4-(2-methoxyethoxy)benzyl]pyrimidine-2,4-diamine

| image = Tetroxoprim.svg

| tradename =

| pregnancy_AU =

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| CAS_number_Ref = {{cascite|correct|??}}

| CAS_number = 53808-87-0

| ATC_prefix = J01

| ATC_suffix = EE06

| ATC_supplemental = (with sulfadiazine)

| PubChem = 65450

| DrugBank_Ref = {{drugbankcite|correct|drugbank}}

| DrugBank =

| UNII_Ref = {{fdacite|changed|FDA}}

| UNII = 5R6712AY0K

| KEGG_Ref = {{keggcite|correct|kegg}}

| KEGG = D06097

| ChEMBL_Ref = {{ebicite|changed|EBI}}

| ChEMBL = 32039

| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}

| ChemSpiderID = 58910

| chemical_formula =

| C=16 | H=22 | N=4 | O=4

| smiles = COCCOC1=C(C=C(C=C1OC)CC2=CN=C(N=C2N)N)OC

| StdInChI_Ref = {{stdinchicite|changed|chemspider}}

| StdInChI = 1S/C16H22N4O4/c1-21-4-5-24-14-12(22-2)7-10(8-13(14)23-3)6-11-9-19-16(18)20-15(11)17/h7-9H,4-6H2,1-3H3,(H4,17,18,19,20)

| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}

| StdInChIKey = WSWJIZXMAUYHOE-UHFFFAOYSA-N

}}

Tetroxoprim (INN) is a derivative of trimethoprim. It was first described in 1979.{{cite journal |vauthors=Aschhoff HS, Vergin H |title=Tetroxoprim—a new inhibitor of bacterial dihydrofolate reductase |journal=J Antimicrob Chemother |volume=5 |issue=B |pages=19–25 |date=November 1979 |pmid=43863 |doi= 10.1093/jac/5.supplement_b.19}}

Its chemical formula is C=16 | H=22 | N=4 | O=4. {{Cite web|url=https://pubchem.ncbi.nlm.nih.gov/compound/65450|title=Tetroxoprim|website=pubchem.ncbi.nlm.nih.gov}}{{Cite web|url=https://www.sciencedirect.com/topics/nursing-and-health-professions/tetroxoprim|title=Tetroxoprim - an overview | ScienceDirect Topics|website=www.sciencedirect.com}}

References

{{Reflist}}

{{Sulfonamides and trimethoprim}}

Category:Bacterial dihydrofolate reductase inhibitors

Category:Aminopyrimidines

Category:Phenol ethers

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