thiazepine
{{distinguish|diazepine}}
Image:Diltiazem Structural Formulae V.1.svg. 1,4-thiazepine is the seven membered ring in the middle.]]
Thiazepines are substituted thiepins, with a nitrogen replacing a carbon in the seven-membered heterocyclic compound.{{Cite web |title=MeSH Browser |url=https://meshb.nlm.nih.gov/record/ui?name=Thiazepines |access-date=2022-11-24 |website=meshb.nlm.nih.gov}} Depending on the location of the nitrogen, one distinguishes 1,3-thiazepine and 1,4-thiazepine.
Benzothiazepines have a single benzene attached to the ring, while dibenzothiazepines have two. Diltiazem, a benzothiazepine, is a calcium channel blocker intermediate in properties between verapamil and the dihydropyridines. It is used to treat variant angina (Prinzmetal's angina), either naturally occurring or drug-induced and stable angina.
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