thienobenzodiazepine

{{Short description|Class of chemical compounds}}

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{{distinguish|thienodiazepine|thienotriazolodiazepine}}

File:Examples of thienobenzodiazepines.svg

Thienobenzodiazepine is a heterocyclic compound containing a diazepine ring fused to a thiophene ring and a benzene ring. Thienobenzodiazepine forms the central core of pharmaceutical drugs including atypical antipsychotic olanzapine (Zyprexa) and antimuscarinic telenzepine. Thienobenzodiazepines act relatively selectively at the α₂ subunit of the GABA_A receptor.{{Cite journal |last1=Bymaster |first1=Frank P |last2=Calligaro |first2=David O |last3=Falcone |first3=Julie F |last4=Marsh |first4=Richard D |last5=Moore |first5=Nicholas A |last6=Tye |first6=Nicholas C |last7=Seeman |first7=Philip |author-link7=Philip Seeman |last8=Wong |first8=David T |author-link8=David T. Wong |date=February 1996 |title=Radioreceptor Binding Profile of the Atypical Antipsychotic Olanzapine |url=https://pubmed.ncbi.nlm.nih.gov/8822531/ |journal=Neuropsychopharmacology |volume=4 |issue=2 |pages=87–96 |doi=10.1016/0893-133X(94)00129-N |pmid=8822531 |via=PubMed}}