thiram

{{chembox

| Verifiedfields = changed

| Watchedfields = changed

| verifiedrevid = 437410135

| ImageFile = Thiuram.svg

| ImageAlt = Structural formula of thiram

| ImageFile1 = Thiram-3D-balls.png

| ImageSize1 = 200

| ImageAlt1 = Ball-and-stick model of the thiram molecule

| PIN = Dimethylcarbamothioic dithioperoxyanhydride

| OtherNames =

|Section1={{Chembox Identifiers

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = 0D771IS0FH

| CASNo_Ref = {{cascite|correct|CAS}}

| CASNo = 137-26-8

| PubChem = 5455

| KEGG_Ref = {{keggcite|correct|kegg}}

| KEGG = D06114

| ChEBI_Ref = {{ebicite|changed|EBI}}

| ChEBI = 9495

| SMILES = CN(C)C(=S)SSC(=S)N(C)C

| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}

| ChemSpiderID = 5256

| InChI = 1/C6H12N2S4/c1-7(2)5(9)11-12-6(10)8(3)4/h1-4H3

| InChIKey = KUAZQDVKQLNFPE-UHFFFAOYAK

| StdInChI_Ref = {{stdinchicite|changed|chemspider}}

| StdInChI = 1S/C6H12N2S4/c1-7(2)5(9)11-12-6(10)8(3)4/h1-4H3

| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}

| StdInChIKey = KUAZQDVKQLNFPE-UHFFFAOYSA-N

}}

|Section2={{Chembox Properties

| C=6 | H=12 | N=2 | S=4

| Appearance= White to yellow crystalline powder

| Odor = Characteristic{{vague|date=June 2019}}

| Density=1.29 g/cm³

| MeltingPtC=155 to 156

| BoilingPt=

| BoilingPt_notes = decomposes

| Solubility=30 mg/L

| VaporPressure = 0.000008 mmHg (20 °C)

}}

|Section6={{Chembox Pharmacology

| ATCCode_prefix = P03

| ATCCode_suffix = AA05

}}

|Section7={{Chembox Hazards

| MainHazards=

| FlashPt={{convert|138|C|F}}U.S. Department of Agriculture, Soil Conservation Service. 1990 (Nov). SCS/ARS/CES Pesticide Properties Database: Version 2.0 (Summary). USDA - Soil Conservation Service, Syracuse, NY.

| AutoignitionPt =

| PEL = TWA 5 mg/m³{{PGCH|0612}}

| IDLH = 100 mg/m³

| REL = TWA 5 mg/m³

| LC50 = 500 mg/m³ (rat, 4 hr){{IDLH|137268|Thiram}}

| LD50 = 1350 mg/kg (mouse, oral)
210 mg/kg (rabbit, oral)
560 mg/kg (rat, oral)

}}

}}

Thiram is the simplest thiuram disulfide and the oxidized dimer of dimethyldithiocarbamate. It is used as a fungicide, ectoparasiticide to prevent fungal diseases in seed and crops and similarly as an animal repellent to protect fruit trees and ornamentals from damage by rabbits, rodents and deer. It is effective against Stem gall of coriander, damping off, smut of millet, neck rot of onion, etc. Thiram has been used in the treatment of human scabies, as a sun screen and as a bactericide applied directly to the skin or incorporated into soap.{{cite web | url = http://pmep.cce.cornell.edu/profiles/extoxnet/pyrethrins-ziram/thiram-ext.html | title = Thiram | publisher = Extension Toxicology Network}}

Thiram is also used as a sulfur source and secondary accelerator the sulfur vulcanization of rubbers.