tigloidine

{{Short description|Chemical compound}}

{{cs1 config|name-list-style=vanc}}

{{Drugbox

|drug_name=Tigloidine

|tradename=Tropigline

|image=Tigloidine.svg

|PubChem=5281865

|ChemSpiderID=16736065

|CAS_number=495-83-0

| CAS_number_Ref = {{Cascite|correct|CAS}}

| ChEMBL = 2107120

| KEGG = C10868

| ChEBI = 9593

| UNII = 75GK1SV4EI

| IUPAC_name = (8-Methyl-8-azabicyclo[3.2.1]octan-3-yl) (E)-2-methylbut-2-enoate

| C=13 | H=21 | N=1 | O=2

| SMILES = CC=C(C)C(=O)OC1CC2CCC(C1)N2C

| StdInChI = 1S/C13H21NO2/c1-4-9(2)13(15)16-12-7-10-5-6-11(8-12)14(10)3/h4,10-12H,5-8H2,1-3H3/b9-4+

| StdInChIKey = UVHGSMZRSVGWDJ-RUDMXATFSA-N

}}

Tigloidine is a tropane alkaloid that naturally occurs as a minor constituent of a number of solanaceous plants, including Duboisia myoporoides,{{cite journal |doi=10.1039/JR9370001820|title=383. The minor alkaloids of Duboisia myoporoides|year=1937| vauthors = Barger G, Martin WF, Mitchell W |journal=Journal of the Chemical Society (Resumed)|page=1820|hdl=1842/35366|hdl-access=free}} Physalis peruviana,{{cite journal |doi=10.1016/0031-9422(74)85016-8|title=Biosynthesis of ticloidine in Physalis peruviana|year=1974| vauthors = Beresford PJ, Woolley JG |journal=Phytochemistry |volume=13 |issue=10 |pages=2143–2144 |bibcode=1974PChem..13.2143B }} and Mandragora turcomanica.

It was formerly marketed as an antiparkinsonian drug{{cite journal |pmc=2028565|year=1958|title=Approved Names|journal=British Medical Journal|volume=1|issue=5080|page=1175|doi=10.1136/bmj.1.5080.1175}} under the trade name Tropigline.{{cite book|title=Index Nominum 2000: International Drug Directory|url=https://books.google.com/books?id=5GpcTQD_L2oC&pg=PA1419|year=2000|publisher=Taylor & Francis|isbn=978-3-88763-075-1|pages=1663–}}