tolpropamine

{{Short description|Chemical compound}}

{{cs1 config|name-list-style=vanc}}

{{Drugbox

| verifiedrevid = 437200296

| IUPAC_name = N,N-dimethyl-3-(4-methylphenyl)-3-phenylpropan-1-amine

| image = Tolpropamine.svg

| tradename =

| pregnancy_category =

| legal_status =

| routes_of_administration =

| bioavailability =

| protein_bound =

| metabolism =

| elimination_half-life =

| excretion =

| CAS_number = 5632-44-0

| CAS_supplemental = {{CAS|3354-67-4}}

| ATC_prefix = D04

| ATC_suffix = AA12

| PubChem = 72141

| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}

| ChemSpiderID = 65115

| UNII_Ref = {{fdacite|correct|FDA}}

| UNII = TBZ8909KFS

| KEGG_Ref = {{keggcite|correct|kegg}}

| KEGG = D07196

| C=18 | H=23 | N=1

| smiles = c1cc(ccc1C(c2ccccc2)CCN(C)C)C

| StdInChI_Ref = {{stdinchicite|correct|chemspider}}

| StdInChI = 1S/C18H23N/c1-15-9-11-17(12-10-15)18(13-14-19(2)3)16-7-5-4-6-8-16/h4-12,18H,13-14H2,1-3H3

| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}

| StdInChIKey = CINROOONPHQHPO-UHFFFAOYSA-N

}}

Tolpropamine is an antihistamine and anticholinergic used as an antipruritic.{{cite book | vauthors = Kutscher B | chapter = Dermatologicals (D), 2. Antifungals (D01), Emollients and Protectives (D02), and Antipruritics (D04) for Dermatological Use | veditors = Ley C |title=Ullmann's Encyclopedia of Industrial Chemistry |date=2000-06-15 | pages = 1–24 |doi=10.1002/14356007.w08_w01 | isbn = 978-3-527-30385-4 | s2cid = 225510885 }}