ureidopenicillin
{{Short description|Group of chemical compounds}}
File:Azlocillin skeletal.svg]]
The ureidopenicillins are a group of penicillins which are active against Pseudomonas aeruginosa.{{cn|date=January 2023}}
There are three ureidopenicillins in clinical use:{{cite web |url=http://www.mayoclinicproceedings.com/inside.asp?AID=2547 |title=Mayo Clinic Proceedings |access-date=2008-12-26 |archive-date=2020-05-26 |archive-url=https://web.archive.org/web/20200526170856/http://www.mayoclinicproceedings.com/inside.asp?AID=2547 |url-status=dead }}
They are mostly ampicillin derivatives in which the amino acid side chain has been converted to a variety of cyclic ureas. It is speculated that the added side chain mimics a longer segment of the peptidoglycan chain, more than ampicillin, and thus would bind more easily to the penicillin-binding proteins. Ureidopenicillins are not resistant to beta-lactamases.{{cn|date=January 2023}}
They are used parenterally, and are particularly indicated in infections caused by Gram-negative bacteria.{{cn|date=January 2023}}