uronate dehydrogenase

{{Short description|Class of enzymes}}

{{infobox enzyme

| Name = uronate dehydrogenase

| EC_number = 1.1.1.203

| CAS_number = 37250-98-9

| GO_code = 0050388

| image =

| width =

| caption =

}}

In enzymology, an uronate dehydrogenase ({{EC number|1.1.1.203}}) is an enzyme that catalyzes the chemical reaction

:D-galacturonate + NAD⁺ + H₂O $\backslash rightleftharpoons$ {{chem name|D-galactaro-1,5-lactone}} + NADH + H⁺

The 3 substrates of this enzyme are D-galacturonate, NAD⁺, and H₂O, whereas its 3 products are {{chem name|D-galactaro-1,5-lactone}} (the lactone of D-galactarate), NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is uronate:NAD⁺ 1-oxidoreductase. Other names in common use include uronate: NAD-oxidoreductase, and uronic acid dehydrogenase.