xanthotoxol
{{Chembox
| ImageFile = Xanthotoxol.png
| ImageSize = 250px
| ImageAlt = Chemical structure of xanthotoxol.
| IUPACName = 9-Hydroxy-7H-furo[3,2-g][1]benzopyran-7-one
| OtherNames = 8-Hydroxypsoralen
8-Hydroxypsoralene
8-Hydroxyfuranocoumarin
|Section1={{Chembox Identifiers
| CASNo = 2009-24-7
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 8RL486L8A5
| PubChem = 65090
| SMILES = C1=CC(=O)OC2=C(C3=C(C=CO3)C=C21)O
| ChemSpiderID = 58600
| InChI = 1/C11H6O4/c12-8-2-1-6-5-7-3-4-14-10(7)9(13)11(6)15-8/h1-5,13H
| InChIKey = JWVYQQGERKEAHW-UHFFFAOYAF
| StdInChI = 1S/C11H6O4/c12-8-2-1-6-5-7-3-4-14-10(7)9(13)11(6)15-8/h1-5,13H
| StdInChIKey = JWVYQQGERKEAHW-UHFFFAOYSA-N
}}
|Section2={{Chembox Properties
| Formula = C11H6O4
| MolarMass = 202.16 g/mol
| Appearance =
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|Section3={{Chembox Hazards
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Xanthotoxol is a furanocoumarin. It is one of the major active ingredients in Cnidium monnieri.Xanthotoxol exerts neuroprotective effects via suppression of the inflammatory response in a rat model of focal cerebral ischemia. He W, Chen W, Zhou Y, Tian Y and Liao F, Cell Mol Neurobiol., July 2013, volume 33, issue 5, pages 715-722, {{doi|10.1007/s10571-013-9939-2}}
Metabolism
- Xanthotoxol O-methyltransferase (8-hydroxyfuranocoumarin 8-O-methyltransferase) is an enzyme that uses S-adenosyl methionine and xanthotoxol to produce S-adenosylhomocysteine and O-methylxanthotoxol (xanthotoxin or methoxsalen).